MRI of healthy brain aging: A review

ME MacDonald, GB Pike - NMR in Biomedicine, 2021 - Wiley Online Library
We present a review of the characterization of healthy brain aging using MRI with an
emphasis on morphology, lesions, and quantitative MR parameters. A scope review found …

The role of neutrophils in the dysfunction of central nervous system barriers

B Santos-Lima, EC Pietronigro, E Terrabuio… - Frontiers in Aging …, 2022 - frontiersin.org
Leukocyte migration into the central nervous system (CNS) represents a central process in
the development of neurological diseases with a detrimental inflammatory component …

Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans

V Fleischer, G Gonzalez-Escamilla… - Proceedings of the …, 2021 - National Acad Sciences
Neuroinflammation is a pathophysiological hallmark of multiple sclerosis and has a close
mechanistic link to neurodegeneration. Although this link is potentially targetable, robust …

Characterization of age-related differences in the human choroid plexus volume, microstructural integrity, and blood perfusion using multiparameter magnetic …

JSR Alisch, M Kiely, C Triebswetter… - Frontiers in Aging …, 2021 - frontiersin.org
The choroid plexus (CP) is an important cerebral structure involved in cerebrospinal fluid
production and transport of solutes into the brain. Recent studies have uncovered the …

The molecular anatomy and functions of the choroid plexus in healthy and diseased brain

I Kratzer, J Ek, H Stolp - Biochimica et Biophysica Acta (BBA) …, 2020 - Elsevier
The choroid plexus (CP) is located in the ventricular system of the brain (one in each
ventricle), and the CP epithelial cells form an important barrier between the blood and the …

[HTML][HTML] Association of plasma markers of Alzheimer's disease, neurodegeneration, and neuroinflammation with the choroid plexus integrity in aging

M Bouhrara, KA Walker, JSR Alisch, Z Gong… - Aging and …, 2024 - pmc.ncbi.nlm.nih.gov
The choroid plexus (CP) is a vital brain structure essential for cerebrospinal fluid (CSF)
production. Moreover, alterations in the CP's structure and function are implicated in …

Clinical imaging of choroid plexus in health and in brain disorders: a mini-review

V Hubert, F Chauveau, C Dumot, E Ong… - Frontiers in molecular …, 2019 - frontiersin.org
The choroid plexuses (ChPs) perform indispensable functions for the development,
maintenance and functioning of the brain. Although they have gained considerable interest …

Choroid plexuses at the interface of peripheral immunity and tissue repair in multiple sclerosis

VAG Ricigliano, B Stankoff - Current Opinion in Neurology, 2023 - journals.lww.com
ChP imaging metrics are emerging as possible biomarkers of neuroinflammation and repair
failure in MS. Future works combining multimodal imaging techniques should provide a …

Differences in the choroid plexus volume and microstructure are associated with body adiposity

JSR Alisch, JM Egan, M Bouhrara - Frontiers in Endocrinology, 2022 - frontiersin.org
The choroid plexus (CP) is a cerebral structure located in the ventricles that functions in
producing most of the brain's cerebrospinal fluid (CSF) and transporting proteins and …

Improving choroid plexus segmentation in the healthy and diseased brain: relevance for tau-PET imaging in dementia

E Tadayon, B Moret, G Sprugnoli… - Journal of …, 2020 - content.iospress.com
Recent studies have revealed the possible role of choroid plexus (ChP) in Alzheimer's
disease (AD). T1-weighted MRI is the modality of choice for the segmentation of ChP in …