Cellular function is controlled through intricate networks of signals, which lead to the myriad
pathways governing cell fate. Fluorescent biosensors have enabled the study of these …

Potassium ion (K+) is the most abundant metal ion in cells and plays an indispensable role
in practically all biological systems. Although there have been reports of both synthetic and …

Highlights•Boom of genetically encoded fluorescent biosensors to illuminate anions in
biology.•Approaches to design and engineer anion biosensors.•Biosensors for chloride …

The development of new or improved single fluorescent protein (FP)-based biosensors
(SFPBs), particularly those with excitation and emission at near-infrared wavelengths, is …

In this study, a novel transcription factor and aptamer-based sandwich assay is proposed to
detect L-lactate in biofluids with excellent selectivity and sensitivity. The assay employs an L …

The growing demand for glycolate, fueled by economic development, requires the
advancement of production methods. Escherichia coli (E. coli), a preferred host for glycolate …

We report the development of amperometric biosensors (ABSs) employing flavocytochrome
b 2 (Fc b 2) coupled with nanoparticles (NPs) of noble metals on graphite electrode (GE) …

As a critical metabolite, the standardization of lactate quantification is increasingly crucial.
Therefore, we developed LaconicSF, a lactate-responsive biosensor exhibiting exceptional …

Malonyl-CoA is the essential building block of fatty acids and regulates cell function through
protein malonylation and allosteric regulation of signaling networks. Accordingly, the …

Inhibitors of ʟ‐lactate transport are in development as a novel mode of action in antitumor
therapy and malaria. Previously, we used radiolabeled ʟ‐lactate to assay transport via the …