Solid-state nanopore sensors

L Xue, H Yamazaki, R Ren, M Wanunu… - Nature Reviews …, 2020 - nature.com
Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …

In situ solid-state nanopore fabrication

JP Fried, JL Swett, BP Nadappuram, JA Mol… - Chemical Society …, 2021 - pubs.rsc.org
Nanopores in solid-state membranes are promising for a wide range of applications
including DNA sequencing, ultra-dilute analyte detection, protein analysis, and polymer data …

Solid-state nanopore fabrication by automated controlled breakdown

M Waugh, K Briggs, D Gunn, M Gibeault, S King… - Nature …, 2020 - nature.com
Solid-state nanopores are now well established as single-biomolecule sensors that hold
great promise as sensing elements in diagnostic and sequencing applications. However …

Plasmonic‐nanopore biosensors for superior single‐molecule detection

JD Spitzberg, A Zrehen, XF van Kooten… - Advanced …, 2019 - Wiley Online Library
Plasmonic and nanopore sensors have separately received much attention for achieving
single‐molecule precision. A plasmonic “hotspot” confines and enhances optical excitation …

Biomimetic potassium-selective nanopores

ET Acar, SF Buchsbaum, C Combs, F Fornasiero… - Science …, 2019 - science.org
Reproducing the exquisite ion selectivity displayed by biological ion channels in artificial
nanopore systems has proven to be one of the most challenging tasks undertaken by the …

Solid-state and polymer nanopores for protein sensing: A review

N Meyer, I Abrao-Nemeir, JM Janot, J Torrent… - Advances in colloid and …, 2021 - Elsevier
In two decades, the solid state and polymer nanopores became attractive method for the
protein sensing with high specificity and sensitivity. They also allow the characterization of …

Photothermally assisted thinning of silicon nitride membranes for ultrathin asymmetric nanopores

H Yamazaki, R Hu, Q Zhao, M Wanunu - ACS nano, 2018 - ACS Publications
Sculpting solid-state materials at the nanoscale is an important step in the manufacturing of
numerous types of sensor devices, in particular solid-state nanopore sensors. Here we …

Formation of single nanopores with diameters of 20–50 nm in silicon nitride membranes using laser-assisted controlled breakdown

C Ying, J Houghtaling, OM Eggenberger, A Guha… - ACS …, 2018 - ACS Publications
Nanopores with diameters from 20 to 50 nm in silicon nitride (SiN x) windows are useful for
single-molecule studies of globular macromolecules. While controlled breakdown (CBD) is …

Stable fabrication of a large nanopore by controlled dielectric breakdown in a high-pH solution for the detection of various-sized molecules

I Yanagi, R Akahori, K Takeda - Scientific reports, 2019 - nature.com
For nanopore sensing of various-sized molecules with high sensitivity, the size of the
nanopore should be adjusted according to the size of each target molecule. For solid-state …

Nanopore Formation via Tip‐Controlled Local Breakdown Using an Atomic Force Microscope

Y Zhang, Y Miyahara, N Derriche, W Yang… - Small …, 2019 - Wiley Online Library
The dielectric breakdown approach for forming nanopores has greatly accelerated the pace
of research in solid‐state nanopore sensing, enabling inexpensive formation of nanopores …