Long COVID endotheliopathy: hypothesized mechanisms and potential therapeutic approaches

J Ahamed, J Laurence - The Journal of clinical investigation, 2022 - Am Soc Clin Investig
SARS-CoV-2–infected individuals may suffer a multi–organ system disorder known as “long
COVID” or post-acute sequelae of SARS-CoV-2 infection (PASC). There are no standard …

Human organoid models to study SARS-CoV-2 infection

Y Han, L Yang, LA Lacko, S Chen - Nature Methods, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is one of the deadliest pandemics in history. SARS …

SARS-CoV-2 infection induces ferroptosis of sinoatrial node pacemaker cells

Y Han, J Zhu, L Yang, BE Nilsson-Payant… - Circulation …, 2022 - Am Heart Assoc
Background: Increasing evidence suggests that cardiac arrhythmias are frequent clinical
features of coronavirus disease 2019 (COVID-19). Sinus node damage may lead to …

COVID-19 and the vasculature: current aspects and long-term consequences

B Martinez-Salazar, M Holwerda, C Stuedle… - Frontiers in cell and …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was first identified in
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …

Role of CCL2/CCR2 axis in the pathogenesis of COVID-19 and possible Treatments: All options on the Table

M Ranjbar, A Rahimi, Z Baghernejadan… - International …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …

Long-term effect of SARS-CoV-2 infection on cardiovascular outcomes and all-cause mortality

A Aleksova, AL Fluca, G Gagno, A Pierri, L Padoan… - Life sciences, 2022 - Elsevier
Since the very beginning of the coronavirus disease 2019 (COVID-19) pandemic in early
2020, it was evident that patients with cardiovascular disease (CVD) were at an increased …

Viral myocarditis—from pathophysiology to treatment

HP Schultheiss, C Baumeier, G Aleshcheva… - Journal of Clinical …, 2021 - mdpi.com
The diagnosis of acute and chronic myocarditis remains a challenge for clinicians.
Characterization of this disease has been hampered by its diverse etiologies and …

[HTML][HTML] Interaction of SARS-CoV-2 with cardiomyocytes: Insight into the underlying molecular mechanisms of cardiac injury and pharmacotherapy

A Abdi, S AlOtaiby, F Al Badarin, A Khraibi… - Biomedicine & …, 2022 - Elsevier
SARS-CoV-2 causes respiratory illness with a spectrum of systemic complications. However,
the mechanism for cardiac infection and cardiomyocyte injury in COVID-19 patients remains …

Role of chemokine systems in cancer and inflammatory diseases

H Li, M Wu, X Zhao - MedComm, 2022 - Wiley Online Library
Chemokines are a large family of small secreted proteins that have fundamental roles in
organ development, normal physiology, and immune responses upon binding to their …

[HTML][HTML] Manifestations and mechanism of SARS-CoV2 mediated cardiac injury

S Xu, W Wu, S Zhang - International Journal of Biological Sciences, 2022 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), a global pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV2) had resulted in considerable morbidity …