Although there has been substantial improvement in atherosclerotic cardiovascular disease
(ASCVD) outcomes in recent decades, ASCVD remains the leading cause of morbidity and …

Atherosclerosis is a leading cause of vascular disease worldwide. Its major clinical
manifestations include ischemic heart disease, ischemic stroke, and peripheral arterial …

Purpose. Conduct a systematic umbrella review to evaluate the relationship of physical
activity (PA) with all-cause mortality, cardiovascular mortality, and incident cardiovascular …

Background The relationships between physical activity (PA) and both cardiovascular
disease (CVD) and type 2 diabetes mellitus (T2 DM) have predominantly been estimated …

Objective Recent evidence suggests the existence of a physical activity paradox, with
beneficial health outcomes associated with leisure time physical activity, but detrimental …

Objective To investigate the association between active commuting and incident
cardiovascular disease (CVD), cancer, and all cause mortality. Design Prospective …

Background No reviews have quantified the specific amounts of physical activity required for
lower risks of coronary heart disease when assessing the dose-response relation. Instead …

In order to update and improve available evidence on associations of physical activity (PA)
with cardiovascular disease (CVD) by applying meta-analytic random effects modeling to …

Objectives Emerging evidence suggests contrasting health effects for leisure-time and
occupational physical activity. In this systematic review, we synthesized and described the …

Background The dose–response relation between physical activity and all-cause mortality is
not well defined at present. We conducted a systematic review and meta-analysis to …