Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal
survival and growth. The signaling cascades initiated by BDNF and its receptor are the key …

The current mainstay treatment of Parkinson's disease (PD) consists of dopamine
replacement therapy which, in addition to causing several side effects, does not delay …

Background Accumulating evidence suggests that neuroinflammation plays an important
role in the progression of Parkinson's disease (PD). Excessively activated microglia produce …

Parkinson's disease (PD) is a common neurodegenerative disease characterized by
selective loss of dopaminergic neurons in the substantia nigra (SN). Neuroinflammation …

The nerve growth factor (NGF) is essential for the survival of both peripheral ganglion cells
and central cholinergic neurons in the basal forebrain. The accelerated loss of central …

Background Accumulating evidence suggests that inflammation plays an important role in
the progression of Parkinson's disease (PD). Among many inflammatory factors found in the …

Parkinson's disease was first described in 1817 by James Parkinson. It is one of the most
common neurodegenerative disorders, affecting the nigrostriatal pathways involved in the …

Objective We tested the hypothesis that gene delivery of the trophic factor neurturin could
preserve motor function and protect nigrostriatal circuitry in hemiparkinsonian monkeys …

In the present study, we evaluated anti‐Parkinson's activity of petroleum ether extract of
Ficus religiosa (PEFRE) leaves in haloperidol and 6 hydroxydopamine (6‐OHDA) induced …

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the
progressive loss of dopaminergic nigral neurons and striatal dopamine. Despite the …