Locoregional drug delivery for cancer therapy: Preclinical progress and clinical translation

S Shaha, D Rodrigues, S Mitragotri - Journal of Controlled Release, 2024 - Elsevier
Systemic drug delivery is the current clinically preferred route for cancer therapy. However,
challenges associated with tumor localization and off-tumor toxic effects limit the clinical …

Immunotherapy revolutionizing brain metastatic cancer treatment: personalized strategies for transformative outcomes

T Li, S Sun, Y Li, Y Zhang, L Wei - Frontiers in Immunology, 2024 - frontiersin.org
Brain metastatic cancer poses a significant clinical challenge, with limited treatment options
and poor prognosis for patients. In recent years, immunotherapy has emerged as a …

The effect of the foreign body response on drug elution from subdermal delivery systems

S Capuani, N Hernandez, JN Campa-Carranza… - Biomaterials, 2025 - Elsevier
Contrasting findings are presented in the literature regarding the influence of foreign body
response (FBR) on drug release from implantable drug delivery systems. To this end, here …

Innovative biomedical applications of micro/nano channel technologies in microfluidics

N Shukla, CYC Rodriguez, R Das, E Mukhanova… - Microchemical …, 2024 - Elsevier
The development of microfluidic devices represents a major breakthrough in biological
research. These devices, referred to as analytical microsystems, are engineered for high …