Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration
DW McKellar, LD Walter, LT Song, M Mantri… - Communications …, 2021 - nature.com
Skeletal muscle repair is driven by the coordinated self-renewal and fusion of myogenic
stem and progenitor cells. Single-cell gene expression analyses of myogenesis have been …
stem and progenitor cells. Single-cell gene expression analyses of myogenesis have been …
Plasticity of muscle stem cells in homeostasis and aging
E Porpiglia, HM Blau - Current Opinion in Genetics & Development, 2022 - Elsevier
We are living longer, but our healthspan has not increased. The goal of regenerative
medicine is to increase quality of life through an understanding of the cellular and molecular …
medicine is to increase quality of life through an understanding of the cellular and molecular …
Satellite cell depletion disrupts transcriptional coordination and muscle adaptation to exercise
Satellite cells are required for postnatal development, skeletal muscle regeneration across
the lifespan, and skeletal muscle hypertrophy prior to maturity. Our group has aimed to …
the lifespan, and skeletal muscle hypertrophy prior to maturity. Our group has aimed to …
Extraocular muscle stem cells exhibit distinct cellular properties associated with non-muscle molecular signatures
DD Girolamo, M Benavente-Diaz, M Murolo… - …, 2024 - journals.biologists.com
Skeletal muscle stem cells (MuSCs) are recognised as functionally heterogeneous. Cranial
MuSCs are reported to have greater proliferative and regenerative capacity when compared …
MuSCs are reported to have greater proliferative and regenerative capacity when compared …
Strength in numbers: Large-scale integration of single-cell transcriptomic data reveals rare, transient muscle progenitor cell states in muscle regeneration
DW McKellar, LD Walter, LT Song, M Mantri… - BioRxiv, 2020 - biorxiv.org
Skeletal muscle repair is driven by the coordinated self-renewal and fusion of myogenic
stem and progenitor cells. Single-cell gene expression analyses of myogenesis have been …
stem and progenitor cells. Single-cell gene expression analyses of myogenesis have been …
Enhancing interrogation of skeletal muscle samples for informative quantitative data
TA Partridge - Journal of Neuromuscular Diseases, 2021 - content.iospress.com
Careful quantitative analysis of histological preparations of muscle samples is crucial to
accurate investigation of myopathies in man and of interpretation of data from animals …
accurate investigation of myopathies in man and of interpretation of data from animals …
DETERMINING THE ROLE OF SATELLITE CELLS DURING SKELETAL MUSCLE ADAPTATION
DA Englund - uknowledge.uky.edu
Physical inactivity, advancing age, limb immobilization, degenerative diseases and various
systemic diseases (many cancers, sepsis, HIV, COPD, kidney disease) all lead to skeletal …
systemic diseases (many cancers, sepsis, HIV, COPD, kidney disease) all lead to skeletal …