The immunology of the hygiene hypothesis of allergy is complex and involves the loss of
cellular and humoral immunoregulatory pathways as a result of the adoption of a Western …

Pertussis is a severe respiratory infection caused by Bordetella pertussis, and in 2008,
pertussis was associated with an estimated 16 million cases and 195,000 deaths globally …

CD4+ T cells can either enhance or inhibit tumour immunity. Although regulatory T cells
have long been known to impede antitumour responses,,,–, other CD4+ T cells have …

ABSTRACT Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that
plays a central role in limiting host immune response to pathogens, thereby preventing …

Abstract Interleukin-10 (IL-10), a cytokine with anti-inflammatory properties, has a central
role in infection by limiting the immune response to pathogens and thereby preventing …

Dendritic cells (DCs) are gatekeepers of the immune system that control induction and
polarization of primary, antigen-specific immune responses. Depending on their …

Substantial progress in understanding mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumors, organ transplantation and chronic infections has led to a …

IL-10 is an anti-inflammatory cytokine. During infection it inhibits the activity of Th1 cells, NK
cells, and macrophages, all of which are required for optimal pathogen clearance but also …

▪ Abstract Dendritic cells (DCs) have several functions in innate and adaptive immunity. In
addition, there is increasing evidence that DCs in situ induce antigen-specific …

Although we might shudder at the thought of billions of bacteria living in our lower intestine,
we are colonized by these passengers shortly after birth. However, the relationship is mostly …