[HTML][HTML] SARS-CoV-2 vaccines, vaccine development technologies, and significant efforts in vaccine development during the pandemic: the lessons learned might …
We are currently approaching three years since the beginning of the coronavirus disease
2019 (COVID-19) pandemic. SARS-CoV-2 has caused extensive disruptions in everyday …
2019 (COVID-19) pandemic. SARS-CoV-2 has caused extensive disruptions in everyday …
[HTML][HTML] Bacteriophage T4 head: structure, assembly, and genome packaging
Bacteriophage (phage) T4 has served as an extraordinary model to elucidate biological
structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, portal …
structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, portal …
[HTML][HTML] Engineered reporter phages for detection of Escherichia coli, Enterococcus, and Klebsiella in urine
S Meile, J Du, S Staubli, S Grossmann… - Nature …, 2023 - nature.com
The rapid detection and species-level differentiation of bacterial pathogens facilitates
antibiotic stewardship and improves disease management. Here, we develop a rapid …
antibiotic stewardship and improves disease management. Here, we develop a rapid …
Bacteriophage T4 as a Protein-Based, Adjuvant-and Needle-Free, Mucosal Pandemic Vaccine Design Platform
The COVID-19 pandemic has transformed vaccinology. Rapid deployment of mRNA
vaccines has saved countless lives. However, these platforms have inherent limitations …
vaccines has saved countless lives. However, these platforms have inherent limitations …
[HTML][HTML] Design of bacteriophage T4-based artificial viral vectors for human genome remodeling
Designing artificial viral vectors (AVVs) programmed with biomolecules that can enter
human cells and carry out molecular repairs will have broad applications. Here, we describe …
human cells and carry out molecular repairs will have broad applications. Here, we describe …
A bacteriophage-based, highly efficacious, needle-and adjuvant-free, mucosal COVID-19 vaccine
ABSTRACT The US Food and Drug Administration-authorized mRNA-and adenovirus-
based SARS-CoV-2 vaccines are intramuscularly injected in two doses and effective in …
based SARS-CoV-2 vaccines are intramuscularly injected in two doses and effective in …
Bacteriophage T4 as a nanovehicle for delivery of genes and therapeutics into human cells
VB Rao, J Zhu - Current opinion in virology, 2022 - Elsevier
The ability to deliver therapeutic genes and biomolecules into a human cell and restore a
defective function has been the holy grail of medicine. Adeno-associated viruses and …
defective function has been the holy grail of medicine. Adeno-associated viruses and …
Engineered reporter phages for rapid detection of Escherichia coli, Klebsiella spp., and Enterococcus spp. in urine
S Meile, J Du, S Staubli, S Grossman, H Koliwer-Brandl… - bioRxiv, 2022 - biorxiv.org
The rapid detection and species-level differentiation of bacterial pathogens facilitates
antibiotic stewardship and improves disease management. Here, we develop a rapid …
antibiotic stewardship and improves disease management. Here, we develop a rapid …