The gut microbiota in obesity and weight management: microbes as friends or foe?

M Van Hul, PD Cani - Nature Reviews Endocrinology, 2023 - nature.com
Obesity is caused by a long-term difference between energy intake and expenditure—an
imbalance that is seemingly easily restored by increasing exercise and reducing caloric …

Metabolism and metabolic disorders and the microbiome: the intestinal microbiota associated with obesity, lipid metabolism, and metabolic health—pathophysiology …

J Aron-Wisnewsky, MV Warmbrunn, M Nieuwdorp… - Gastroenterology, 2021 - Elsevier
Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …

Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease in mice

HS Yoon, CH Cho, MS Yun, SJ Jang, HJ You… - Nature …, 2021 - nature.com
The gut microbiota, which includes Akkermansia muciniphila, is known to modulate energy
metabolism, glucose tolerance, immune system maturation and function in humans …

From correlation to causality: the case of Subdoligranulum

M Van Hul, T Le Roy, E Prifti, MC Dao, A Paquot… - Gut …, 2020 - Taylor & Francis
Gut microbes are considered as major factors contributing to human health. Nowadays, the
vast majority of the data available in the literature are mostly exhibiting negative or positive …

Genomic diversity and ecology of human-associated Akkermansia species in the gut microbiome revealed by extensive metagenomic assembly

N Karcher, E Nigro, M Punčochář, A Blanco-Míguez… - Genome biology, 2021 - Springer
Background Akkermansia muciniphila is a human gut microbe with a key role in the
physiology of the intestinal mucus layer and reported associations with decreased body …

Akkermansia muciniphila plays critical roles in host health

Q Zhao, J Yu, Y Hao, H Zhou, Y Hu… - Critical Reviews in …, 2023 - Taylor & Francis
Akkermansia muciniphila, an intestinal microorganism, belongs to Verrucomicrobia, one of
the most abundant microorganisms in the mammalian gut. It is a mucin-degrading bacterium …

Systematic review: gastric microbiota in health and disease

M Rajilic‐Stojanovic, C Figueiredo… - Alimentary …, 2020 - Wiley Online Library
Background Helicobacter pylori is the most infamous constituent of the gastric microbiota
and its presence is the strongest risk factor for gastric cancer and other gastroduodenal …

Short-chain fatty acids, secondary bile acids and indoles: gut microbial metabolites with effects on enteroendocrine cell function and their potential as therapies for …

KE Masse, VB Lu - Frontiers in Endocrinology, 2023 - frontiersin.org
The gastrointestinal tract hosts the largest ecosystem of microorganisms in the body. The
metabolism of ingested nutrients by gut bacteria produces novel chemical mediators that …

[HTML][HTML] Host/microbiota interactions in health and diseases—Time for mucosal microbiology!

N Daniel, E Lécuyer, B Chassaing - Mucosal Immunology, 2021 - Elsevier
During the last 20 years, a new field of research delineating the importance of the microbiota
in health and diseases has emerged. Inappropriate host-microbiota interactions have been …

Chains of evidence from correlations to causal molecules in microbiome-linked diseases

SN Chaudhari, MD McCurry, AS Devlin - Nature chemical biology, 2021 - nature.com
Human-associated microorganisms play a vital role in human health, and microbial
imbalance has been linked to a wide range of disease states. In this Review, we explore …