Nanomedicine in leishmaniasis: A promising tool for diagnosis, treatment and prevention of disease-An update overview

JP Assolini, ACM Carloto, BT da Silva Bortoleti… - European Journal of …, 2022 - Elsevier
Leishmaniasis is a neglected tropical disease that has a wide spectrum of clinical
manifestations, ranging from visceral to cutaneous, with millions of new cases and …

Nano-co-delivery of lipophosphoglycan with soluble and autoclaved leishmania antigens into PLGA nanoparticles: Evaluation of in vitro and in vivo …

OA Tosyali, A Allahverdiyev, M Bagirova… - Materials Science and …, 2021 - Elsevier
The aim of the present study was to encapsulate lipophosphoglycan molecule (LPG) which
is one of the most immunogenic antigens of Leishmania parasites into PLGA nanoparticles …

A new coumarin based Schiff base fluorescence probe for zinc ion

B Arvas, B Ucar, T Acar, MB Arvas, Y Sahin, F Aydogan… - Tetrahedron, 2021 - Elsevier
Herein, a novel coumarin-based fluorescent probe (FS3) was designed, synthesized, and
characterized. It exhibited significant fluorescence quenching in the presence of Zn 2+ ions …

Leishmania vaccine development: A comprehensive review

I Saini, J Joshi, S Kaur - Cellular Immunology, 2024 - Elsevier
Infectious diseases like leishmaniasis, malaria, HIV, tuberculosis, leprosy and filariasis are
responsible for an immense burden on public health systems. Among these, leishmaniasis …

A Chimera of Th1 Stimulatory Proteins of Leishmania donovani Offers Moderate Immunotherapeutic Efficacy with a Th1‐Inclined Immune Response against Visceral …

S Ratnapriya, Keerti, NK Yadav, A Dube… - BioMed Research …, 2021 - Wiley Online Library
Immunotherapy, a treatment based on host immune system activation, has been shown to
provide a substitute for marginally effective conventional chemotherapy in controlling …

Development, Optimization, and in vitro Evaluation of Silybin-loaded PLGA Nanoparticles and Decoration with 5TR1 Aptamer for Targeted Delivery to Colorectal …

SM Rahimnia, M Saeedi, J Akbari… - AAPS …, 2024 - Springer
Chemotherapeutic agents often lack specificity, intratumoral accumulation, and face drug
resistance. Targeted drug delivery systems based on nanoparticles (NPs) mitigate these …

Synthesis of novel coumarin-triazole hybrids and first evaluation of the 4-phenyl substituted hybrid loaded PLGA nanoparticles delivery system to the anticancer …

B Arvas, B Ucar, T Acar, HS Varli, MB Arvas… - …, 2024 - iopscience.iop.org
Despite the discovery of many chemotherapeutic drugs that prevent uncontrolled cell
division processes in the last century, many studies are still being carried out to develop …

Development, Characterization and In Vitro Gastrointestinal Release of PLGA Nanoparticles Loaded with Full-Spectrum Cannabis Extracts

A Villate, GP Barreto, MS Nicolás… - AAPS …, 2024 - Springer
Cannabinoids, such as∆ 9-tetrahydrocannabinol (THC) and cannabidiol (CBD), are effective
bioactive compounds that improve the quality of life of patients with certain chronic …

Choline Chloride Encapsulated PLGA Nanoparticles Labelled with Lanthanide Metals

B Uçar - Avrupa Bilim ve Teknoloji Dergisi - dergipark.org.tr
Herein, choline chloride was loaded into PLGA nanoparticles to ensure its controlled
release. Encapsulation efficiencies (EE) and loading capacities (LC) of them were …

Vaccine Design, Nanoparticle Vaccines and Biomaterial Applications

P Misra, S Singh - Systems and Synthetic Immunology, 2020 - Springer
Leishmaniasis is a neglected tropical disease subverting the immune system of the infected
individual. Most of available treatment regimens are associated with various drawbacks …