Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety

MA Hannan, MA Rahman, AAM Sohag, MJ Uddin… - Nutrients, 2021 - mdpi.com
Mounting evidence support the potential benefits of functional foods or nutraceuticals for
human health and diseases. Black cumin (Nigella sativa L.), a highly valued nutraceutical …

Trends in use, pharmacology, and clinical applications of emerging herbal nutraceuticals

EM Williamson, X Liu, AA Izzo - British Journal of …, 2020 - Wiley Online Library
The nutraceuticals market is vast, encompassing many different products with inconsistent
levels of evidence available to support their use. This overview represents a Western …

Nigella plants–Traditional uses, bioactive phytoconstituents, preclinical and clinical studies

B Salehi, C Quispe, M Imran, I Ul-Haq… - Frontiers in …, 2021 - frontiersin.org
Nigella is a small genus of the family Ranunculaceae, which includes some popular species
due to their culinary and medicinal properties, especially in Eastern Europe, Middle East …

Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials

A Akbari, GR Mobini, S Agah, M Morvaridzadeh… - European journal of …, 2020 - Springer
Purpose Oxidative stress (OS) is associated with several chronic complications and
diseases. The use of coenzyme Q10 (CoQ10) as an adjuvant treatment with routine clinical …

Functional foods modulating inflammation and metabolism in chronic diseases: a systematic review

J Luvián-Morales, FO Varela-Castillo… - Critical Reviews in …, 2022 - Taylor & Francis
Chronic diseases are responsible for approximately 71% global deaths. These are
characterized by chronic low-grade inflammation and metabolic alterations.“Functional …

The Influence of Nutritional Intervention in the Treatment of Hashimoto's Thyroiditis—A Systematic Review

K Osowiecka, J Myszkowska-Ryciak - Nutrients, 2023 - mdpi.com
Diet can be a complementary treatment for Hashimoto's disease by affecting thyroid function
and anti-inflammatory properties. It is still unclear which dietary strategy would be the most …

The effect of Nigella sativa (black seed) on biomarkers of inflammation and oxidative stress: an updated systematic review and meta-analysis of randomized …

Z Kavyani, V Musazadeh, S Golpour-Hamedani… - …, 2023 - Springer
Objective This study was conducted to assess the effect of Nigella sativa (N. sativa)
supplementation on inflammatory and oxidative markers among the adult population …

Effect of Nigella Sativa Oil on Oxidative Stress, Inflammatory, and Glycemic Control Indices in Diabetic Hemodialysis Patients: A Randomized Double‐Blind …

A Rahmani, B Niknafs, M Naseri… - Evidence‐Based …, 2022 - Wiley Online Library
Background and Aims. Diabetes is a leading cause of renal failure. High levels of oxidative
stress and inflammation in patients with renal diabetes lead to various disorders and …

[HTML][HTML] Nigella sativa oil restores hormonal levels, and endocrine signals among thyroid, ovarian, and uterine tissues of female Wistar rats following sodium fluoride …

MM Elghareeb, GE Elshopakey, S Rezk, A Ateya… - Biomedicine & …, 2024 - Elsevier
The current study aimed to explore the possible prophylactic and therapeutic effect of
Nigella sativa L. oil (NSO) against disruption of endocrine signals and injuries in the thyroid …

Therapeutic potential of thymoquinone in triple-negative breast cancer prevention and progression through the modulation of the tumor microenvironment

GM Adinew, E Taka, B Mochona, RB Badisa… - Nutrients, 2021 - mdpi.com
To date, the tumor microenvironment (TME) has gained considerable attention in various
areas of cancer research due to its role in driving a loss of immune surveillance and …