Purpose Although doxorubicin chemotherapy is commonly applied for treating different
malignant tumors, cardiotoxicity induced by this chemotherapeutic agent restricts its clinical …

Background Drug-induced liver injury (DILI) is the most challenging and thought-provoking
liver problem for hepatologists owing to unregulated medication usage in medical practices …

Alzheimer's disease (AD) is a worldwide rapidly growing neurodegenerative disease. Here,
we elucidated the neuroprotective effects of silymarin (SM) on the hippocampal tissues of …

Alcohol consumption increases the risk of gastritis and gastric ulcer. Nutritional alternatives
are considered for relieving the progression of gastric mucosal lesions instead of …

Angiotensin II-related cardiac fibrosis is one of the key pathological changes of the
hypertrophied left ventricle in various heart disease. Irisin was recently reported to confer …

Peptic ulcer disease is a common gastrointestinal tract disorder that affects up to 20% of the
population of the world. Treatment of peptic ulcer remains challenging due to the limited …

Although Periplaneta americana L. and its modern preparation, Kangfuxin liquid, have been
extensively applied for ulcerative diseases in gastrointestinal tract (eg, gastric ulcer (GU) …

Silymarin is a complex extract isolated from the plant Silybum marianum, widely known for
its prominent antioxidant and hepatoprotective effects, although increasing evidences have …

Inflammation is a vital defense mechanism, creating hostile conditions for pathogens,
preventing the spread of tissue infection and repairing damaged tissues in humans and …

We investigated the potential gastroprotective effects of chrysin on indomethacin induced
gastric ulcers in rats. We used six groups of animals: control; indomethacin (Indo); reference …