Cardiovascular disease and thrombosis in HIV infection
MV Perkins, SB Joseph, DP Dittmer… - … , and vascular biology, 2023 - Am Heart Assoc
HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …
Platelet extracellular vesicles in COVID-19: Potential markers and makers
Platelets and platelet extracellular vesicles (pEV) are at the crossroads of coagulation and
immunity. Extracellular vesicles are messengers that not only transmit signals between cells …
immunity. Extracellular vesicles are messengers that not only transmit signals between cells …
Longitudinal trend of plasma concentrations of extracellular vesicles in patients hospitalized for COVID-19
E Campello, CM Radu, C Simion, L Spiezia… - Frontiers in Cell and …, 2022 - frontiersin.org
Plasma concentrations of extracellular vesicles (EVs) originating from cells involved in
COVID-19-associated coagulopathy (CAC), their longitudinal trend and association with …
COVID-19-associated coagulopathy (CAC), their longitudinal trend and association with …
[HTML][HTML] Tissue factor expression, extracellular vesicles, and thrombosis after infection with the respiratory viruses influenza A virus and coronavirus
N Mackman, SP Grover, S Antoniak - Journal of Thrombosis and …, 2021 - Elsevier
Tissue factor (TF) is induced in a variety of cell types during viral infection, which likely
contributes to disseminated intravascular coagulation and thrombosis. TF‐expressing cells …
contributes to disseminated intravascular coagulation and thrombosis. TF‐expressing cells …
Measurement of tissue factor-positive extracellular vesicles in plasma: strengths and weaknesses of current methods
N Mackman, ATA Sachetto… - Current Opinion in …, 2022 - journals.lww.com
We recommend isolating EVs from plasma and measuring TF activity using a functional
assay in the presence and absence of an anti-TF antibody. We do not recommend using …
assay in the presence and absence of an anti-TF antibody. We do not recommend using …
Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells
F Puhm, I Allaeys, E Lacasse, I Dubuc… - Blood …, 2022 - ashpublications.org
Platelets are hyperactivated in coronavirus disease 2019 (COVID-19). However, the
mechanisms promoting platelet activation by severe acute respiratory syndrome coronavirus …
mechanisms promoting platelet activation by severe acute respiratory syndrome coronavirus …
Risk stratification of patients with SARS-CoV-2 by tissue factor expression in circulating extracellular vesicles
J Burrello, E Caporali, LG Gauthier, E Pianezzi… - Vascular …, 2022 - Elsevier
Inflammatory response following SARS-CoV-2 infection results in substantial increase of
amounts of intravascular pro-coagulant extracellular vesicles (EVs) expressing tissue factor …
amounts of intravascular pro-coagulant extracellular vesicles (EVs) expressing tissue factor …
Angiopoietin2 is associated with coagulation activation and tissue factor expression in extracellular vesicles in COVID-19
MS Barbosa, F de Lima, CR Peachazepi Moraes… - Frontiers in …, 2024 - frontiersin.org
Coagulation activation in immunothrombosis involves various pathways distinct from
classical hemostasis, offering potential therapeutic targets to control inflammation-induced …
classical hemostasis, offering potential therapeutic targets to control inflammation-induced …