Dendritic cell-based vaccines against cancer: challenges, advances and future opportunities

C Fu, T Ma, L Zhou, QS Mi, A Jiang - Immunological investigations, 2022 - Taylor & Francis
As the most potent professional antigen presenting cells, dendritic cells (DCs) have the
ability to activate both naive CD4 and CD8 T cells. Recognized for their exceptional ability to …

Single-cell technologies in multiple myeloma: new insights into disease pathogenesis and translational implications

M Chen, J Jiang, J Hou - Biomarker Research, 2023 - Springer
Multiple myeloma (MM) is a hematological malignancy characterized by clonal proliferation
of plasma cells. Although therapeutic advances have been made to improve clinical …

Trial watch: Dendritic cell (DC)-based immunotherapy for cancer

RS Laureano, J Sprooten, I Vanmeerbeerk… - …, 2022 - Taylor & Francis
Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …

BSA‐AIE nanoparticles with boosted ROS generation for immunogenic cell death immunotherapy of multiple myeloma

Z Liu, J Zhang, H Liu, H Shen, N Meng, X Qi… - Advanced …, 2023 - Wiley Online Library
The main obstacle of multiple myeloma (MM) therapy is the compromised immune
microenvironment, which leads to MM relapses and extramedullary disease progression. In …

Biomimetic nanoparticles for DC vaccination: a versatile approach to boost cancer immunotherapy

L Meng, Z Teng, S Yang, N Wang, YH Guan, X Chen… - Nanoscale, 2023 - pubs.rsc.org
Cancer immunotherapy, which harnesses the immune system to fight cancer, has begun to
make a breakthrough in clinical applications. Dendritic cells (DCs) are the bridge linking …

Immunotherapy for prostate cancer: a current systematic review and patient centric perspectives

L Rehman, MH Nisar, W Fatima, A Sarfraz… - Journal of clinical …, 2023 - mdpi.com
Prostate cancer is the most commonly diagnosed cancer in men worldwide, making up 21%
of all cancer cases. With 345,000 deaths per year owing to the disease, there is an urgent …

Dendritic cell vaccine of gliomas: challenges from bench to bed

Y Zheng, X Ma, S Feng, H Zhu, X Chen, X Yu… - Frontiers in …, 2023 - frontiersin.org
Gliomas account for the majority of brain malignant tumors. As the most malignant subtype of
glioma, glioblastoma (GBM) is barely effectively treated by traditional therapies (surgery …

Dendritic cell hybrid nanovaccine for mild heat inspired cancer immunotherapy

C Shi, C Jian, L Wang, C Gao, T Yang, Z Fu… - Journal of …, 2023 - Springer
Cancer therapeutic vaccine can induce antigen-specific immune response, which has
shown great potential in cancer immunotherapy. As the key factor of vaccine, antigen plays a …

A single-cell transcriptomic map of the murine and human multiple myeloma immune microenvironment across disease stages

E Verheye, D Kancheva, H Satilmis… - Journal of Hematology & …, 2024 - Springer
Background The long-term effectiveness of immunotherapies against Multiple Myeloma
(MM) remains elusive, demonstrated by the inevitable relapse in patients. This underscores …

Tumor-associated macrophages and related myelomonocytic cells in the tumor microenvironment of multiple myeloma

SSY Wang, WJ Chng, H Liu, S de Mel - Cancers, 2022 - mdpi.com
Simple Summary Multiple myeloma (MM) is the second-most common blood cancer and is
currently incurable despite recent advances in treatment. The immune cells which are …