Fluorescent nanoparticles for super-resolution imaging
W Li, GS Kaminski Schierle, B Lei, Y Liu… - Chemical …, 2022 - ACS Publications
Super-resolution imaging techniques that overcome the diffraction limit of light have gained
wide popularity for visualizing cellular structures with nanometric resolution. Following the …
wide popularity for visualizing cellular structures with nanometric resolution. Following the …
Caveat fluorophore: an insiders' guide to small-molecule fluorescent labels
JB Grimm, LD Lavis - Nature Methods, 2022 - nature.com
The last three decades have brought a revolution in fluorescence microscopy. The
development of new microscopes, fluorescent labels and analysis techniques has pushed …
development of new microscopes, fluorescent labels and analysis techniques has pushed …
Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
Molecular engineering of NIR‐II fluorophores for improved biomedical detection
The development of fluorophores for the second near‐infrared window (NIR‐II, 1000–1700
nm) represents an emerging, significant, and vibrant field in analytic chemistry, chemical …
nm) represents an emerging, significant, and vibrant field in analytic chemistry, chemical …
Real-time denoising enables high-sensitivity fluorescence time-lapse imaging beyond the shot-noise limit
A fundamental challenge in fluorescence microscopy is the photon shot noise arising from
the inevitable stochasticity of photon detection. Noise increases measurement uncertainty …
the inevitable stochasticity of photon detection. Noise increases measurement uncertainty …
Biomedical applications of quantum dots: overview, challenges, and clinical potential
Despite the massive advancements in the nanomedicines and their associated research,
their translation into clinically-applicable products is still below promises. The latter fact …
their translation into clinically-applicable products is still below promises. The latter fact …
Photobleaching of organic fluorophores: quantitative characterization, mechanisms, protection
AP Demchenko - Methods and applications in fluorescence, 2020 - iopscience.iop.org
Photochemical stability is one of the most important parameters that determine the
usefulness of organic dyes in different applications. This Review addresses key factors that …
usefulness of organic dyes in different applications. This Review addresses key factors that …
Nanometer resolution imaging and tracking of fluorescent molecules with minimal photon fluxes
F Balzarotti, Y Eilers, KC Gwosch, AH Gynnå… - Science, 2017 - science.org
We introduce MINFLUX, a concept for localizing photon emitters in space. By probing the
emitter with a local intensity minimum of excitation light, MINFLUX minimizes the …
emitter with a local intensity minimum of excitation light, MINFLUX minimizes the …
Toward dynamic structural biology: Two decades of single-molecule Förster resonance energy transfer
BACKGROUND Biomolecular mechanisms are typically inferred from static structural
“snapshots” obtained by x-ray crystallography, nuclear magnetic resonance (NMR) …
“snapshots” obtained by x-ray crystallography, nuclear magnetic resonance (NMR) …
Photomediated ring contraction of saturated heterocycles
Saturated heterocycles are found in numerous therapeutics and bioactive natural products
and are abundant in many medicinal and agrochemical compound libraries. To access new …
and are abundant in many medicinal and agrochemical compound libraries. To access new …