Solid lipid nanoparticles: an approach to improve oral drug delivery

N Mendoza-Muñoz, Z Urbán-Morlán… - … of Pharmacy & …, 2021 - journals.library.ualberta.ca
Nanoparticles have shown overall beneficial effects in drug administration. Specifically, solid
lipid nanoparticles (SLN) have emerged as an alternative to polymer-based systems …

Nanocarriers in tuberculosis treatment: challenges and delivery strategies

M Kumar, T Virmani, G Kumar, R Deshmukh… - Pharmaceuticals, 2023 - mdpi.com
The World Health Organization identifies tuberculosis (TB), caused by Mycobacterium
tuberculosis, as a leading infectious killer. Although conventional treatments for TB exist …

Recent advances in PLGA micro/nanoparticle delivery systems as novel therapeutic approach for drug-resistant tuberculosis

L Shao, S Shen, H Liu - Frontiers in bioengineering and …, 2022 - frontiersin.org
Tuberculosis is a severe infectious disease caused by Mycobacterium tuberculosis and is a
significant public health concern globally. The World Health Organization (WHO) …

Carrageenan-stabilized chitosan alginate nanoparticles loaded with ethionamide for the treatment of tuberculosis

S Abdelghany, M Alkhawaldeh, HS AlKhatib - Journal of Drug Delivery …, 2017 - Elsevier
The objective of this work was to prepare ethionamide-loaded, cross linker free, chitosan
alginate nanoparticles stabilized with varying amounts of carrageenan using simple …

Approaches to treating tuberculosis by encapsulating metal ions and anti-mycobacterial drugs utilizing nano-and microparticle technologies

KH Alzahabi, O Usmani, TK Georgiou… - Emerging Topics in …, 2020 - portlandpress.com
Tuberculosis (TB) is caused by a bacterial infection that affects a number of human organs,
primarily the lungs, but also the liver, spleen, and spine, causing key symptoms of fever …

Nano-engineered solutions for extensively drug-resistant tuberculosis (XDR-TB): A novel nanomedicine

D Singh, V Krishna, N Kumari, A Banerjee… - Nano-Structures & Nano …, 2024 - Elsevier
Nano-engineered solutions are revolutionizing the fight against Extensively Drug-Resistant
Tuberculosis (XDR-TB), a major public health challenge resistant to conventional TB drugs …

Harnessing miRNAs: A Novel Approach to Diagnosis and Treatment of Tuberculosis

AS Doghish, AI Abulsoud, YA Nassar… - … of Biochemical and …, 2025 - Wiley Online Library
Mycobacterium tuberculosis (Mtb) complex, responsible for tuberculosis (TB) infection,
continues to be a predominant global cause of mortality due to intricate host‐pathogen …

Nanoweapons against tuberculosis

J Jampílek, K Kráľová - … in Human Health: Challenges and Approaches, 2020 - Springer
The emerging resistance of Mycobacterium tuberculosis and other so-called nontuberculous
mycobacteria to clinically used drugs, including second-and third-choice drugs, and the …

In vitro and in vivo evaluation of dual Clofazimine and Verapamil loaded PLGA nanoparticles

B Kaur, M Kaur, P Ahlawat, S Sharma - Indian Journal of Clinical …, 2023 - Springer
Combination therapy may counter the risk caused by efflux pumps mediated resistance
developed by mycobacteria with a concomitant increase of the bactericidal effect of anti-TB …

A Novel Method for Preparing Uniform-Sized PLGA Microspheres and the Application in Anti-tubercular Drug Delivery

H Lei, J Shi, X Yang, J Li, H Zhang, L Zhang… - Journal of …, 2021 - Springer
Purpose The size was a key factor influencing the drug loading, release, and delivery
efficacies of poly (lactic-co-glycolic) acid (PLGA) microspheres (MS). The purpose of the …