[HTML][HTML] Functional biology and biotechnology of thermophilic viruses

RK Doss, M Palmer, DA Mead… - Essays in …, 2023 - portlandpress.com
Viruses have developed sophisticated biochemical and genetic mechanisms to manipulate
and exploit their hosts. Enzymes derived from viruses have been essential research tools …

Biodiversity of microorganisms in the Baltic Sea: the power of novel methods in the identification of marine microbes

H Mazur-Marzec, AF Andersson… - FEMS Microbiology …, 2024 - academic.oup.com
Until recently, the data on the diversity of the entire microbial community from the Baltic Sea
were relatively rare and very scarce. However, modern molecular methods have provided …

A novel cryptic clostridial peptide that kills bacteria by a cell membrane permeabilization mechanism

M Szadkowska, M Olewniczak, A Kloska… - Microbiology …, 2022 - Am Soc Microbiol
This work reports detailed characteristics of the antimicrobial peptide Intestinalin (P30),
which is derived from the LysC enzyme of Clostridium intestinale strain URNW. The peptide …

[HTML][HTML] Soil Giant Phage: Genome and Biological Characteristics of Sinorhizobium Jumbo Phage

AP Kozlova, VS Muntyan, ME Vladimirova… - International Journal of …, 2024 - mdpi.com
This paper presents the first in-depth research on the biological and genomic properties of
lytic rhizobiophage AP-J-162 isolated from the soils of the mountainous region of Dagestan …

Bacteriophage Lytic Enzyme P9ly as an Alternative Antibacterial Agent Against Antibiotic-Resistant Shigella dysenteriae and Staphylococcus aureus

F Wang, Y Xiao, Y Lu, ZY Deng, XY Deng… - Frontiers in …, 2022 - frontiersin.org
Developing new strategies to replace or supplement antibiotics to combat bacterial infection
is a pressing task in the field of microbiological research. In this study, we report a lytic …

Molecular Characterization of a DNA Polymerase from Thermus thermophilus MAT72 Phage vB_Tt72: A Novel Type-A Family Enzyme with Strong Proofreading …

S Dorawa, O Werbowy, M Plotka… - International Journal of …, 2022 - mdpi.com
We present a structural and functional analysis of the DNA polymerase of thermophilic
Thermus thermophilus MAT72 phage vB_Tt72. The enzyme shows low sequence identity (< …

New insights into the diversity and evolution of the archaeal mobilome from three complete genomes of Saccharolobus shibatae

S Medvedeva, D Brandt… - Environmental …, 2021 - Wiley Online Library
Saccharolobus (formerly Sulfolobus) shibatae B12, isolated from a hot spring in Beppu,
Japan in 1982, is one of the first hyperthermophilic and acidophilic archaeal species to be …

AmiP from hyperthermophilic Thermus parvatiensis prophage is a thermoactive and ultrathermostable peptidoglycan lytic amidase

A Jasilionis, M Plotka, L Wang, S Dorawa… - Protein …, 2023 - Wiley Online Library
Bacteriophages encode a wide variety of cell wall disrupting enzymes that aid the viral
escape in the final stages of infection. These lytic enzymes have accumulated notable …

[PDF][PDF] Crystal structure of DNA polymerase I from Thermus phage G20c

J Ahlqvist, JA Linares-Pastén, A Jasilionis… - … Section D: Structural …, 2022 - journals.iucr.org
This study describes the structure of DNA polymerase I from Thermus phage G20c, termed
PolI_G20c. This is the first structure of a DNA polymerase originating from a group of related …

[HTML][HTML] Novel Lytic Enzyme of Prophage Origin from Clostridium botulinum E3 Strain Alaska E43 with Bactericidal Activity against Clostridial Cells

A Morzywolek, M Plotka, AK Kaczorowska… - International Journal of …, 2021 - mdpi.com
Clostridium botulinum is a Gram-positive, anaerobic, spore-forming bacterium capable of
producing botulinum toxin and responsible for botulism of humans and animals. Phage …