Abstract MicroRNA-34 (miR-34) has been reported to be dysregulated in various human
cancers and regarded as a tumor suppressive microRNA because of its synergistic effect …

Triple-negative breast cancer (TNBC) is defined as a type of breast cancer with lack of
expression of estrogen receptor (ER), progesterone receptor (PR) and HER2 protein. The …

Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …

MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

TGFβ signaling plays crucial role during development and cancer, however the role for
TGFβ signaling in regulating the noncoding part of the human genome in triple negative …

Aims Exosomes hold great promise as bio-inspired delivery vehicles. Mesenchymal stem
cells (MSCs) are recognized for their potential to yield huge quantities of exosomes. We …

Triple-negative breast cancer (TNBC) is a broad collection of breast cancer that tests
negative for estrogen receptors (ER), progesterone receptors (PR), and excess human …

The development of new therapeutic strategies to target triple-negative breast cancer
(TNBC) is in much demand to overcome the roadblocks associated with the existing …

Male infertility is a multifactorial condition influenced by epigenetic regulation, oxidative
stress, and mitochondrial dysfunction. Oxidative stress-induced damage leads to epigenetic …

Biomarkers can be used for diagnosis, prognosis, and prediction in targeted therapy. The
estrogen receptor α (ERα) and human epidermal growth factor receptor 2 (HER2) are …