The virtual physiological human: ten years after

M Viceconti, P Hunter - Annual review of biomedical …, 2016 - annualreviews.org
Biomedical research and clinical practice are struggling to cope with the growing complexity
that the progress of health care involves. The most challenging diseases, those with the …

Microstructurally motivated constitutive modeling of heart failure mechanics

AI Hasaballa, VY Wang, GB Sands, AJ Wilson… - Biophysical journal, 2019 - cell.com
Heart failure (HF) is one of the leading causes of death worldwide. HF is associated with
substantial microstructural remodeling, which is linked to changes in left ventricular …

Modelling cardiac tissue growth and remodelling

VY Wang, JR Hussan, H Yousefi, CP Bradley… - Journal of Elasticity, 2017 - Springer
Cardiac growth and remodelling are key phenomena influencing the physiological
performance of the heart and progression of various cardiac diseases. Our basic knowledge …

A novel micro-to-macro approach for cardiac tissue mechanics

SMH Haddad, A Samani - Computer methods in BiomeChaniCs …, 2017 - Taylor & Francis
For studying cardiac mechanics, hyperelastic anisotropic computational models have been
developed which require the tissue anisotropic and hyperelastic parameters. These …

Transmural remodeling of cardiac microstructure in aged spontaneously hypertensive rats by diffusion tensor MRI

A Giannakidis, GT Gullberg - Frontiers in physiology, 2020 - frontiersin.org
The long-standing high blood pressure (also known as hypertension) overworks the heart.
Microstructural remodeling is a key factor of hypertensive heart disease progression …

Ultrasonic Texture Analysis Identifies Cardiac Microstructural Alterations in Immune-Inflammatory Disease

AC Kwan, T Nguyen, EH Kim, E Demosthenes, G Salto… - medRxiv, 2020 - medrxiv.org
Background Echocardiographic texture analysis using the signal intensity coefficient (SIC)
can identify fibrosis-associated microstructural changes. This approach has not been tested …

Estimation of Spatiotemporal Isotropic and Anisotropic Myocardial Stiffness using Magnetic Resonance Elastography: A Study in Heart Failure

R Mazumder - 2016 - rave.ohiolink.edu
Heart failure (HF), a complex clinical syndrome that is characterized by abnormal cardiac
structure and function; and has been identified as the new epidemic of the 21st century [1] …