In an ageing society, polypharmacy has become a major public health and economic issue.
Overuse of medications, especially in patients with chronic diseases, carries major health …

Cardiovascular disease (CVD) is the leading cause of death worldwide. Platelet activation
and aggregation play a central role in hemostasis and thrombosis. Herbal medicines have …

Background Cardiovascular diseases and especially Acute Coronary Syndrome (ACS)
constitute a major health issue impacting millions of patients worldwide. Being a leading …

Coronary artery disease remains the major cause of mortality worldwide. Antiplatelet drugs
such as acetylsalicylic acid and P2Y12 receptor antagonists are cornerstone treatments for …

Hypertensive individuals are at a high risk of stroke, and thus, prevention of stroke in
hypertensive patients is essential. Metabolomics and lipidomics can be used to identify …

Abstract Shexiang Baoxin Pill (SBP), a traditional Chinese medicine formula, is commonly
used to treat cardiovascular disease (CVD) in China. However, the complexity of …

Clopidogrel is the most common and widely used antiplatelet agent for patients with
coronary artery disease following confirmation by electrocardiographic studies. The …

Introduction: The most common side effect of ticagrelor is dyspnea, which leads to premature
withdrawal of this life-saving medication in 6.5% of patients. Increased chemoreceptors' …

BACKGROUND Management of ticagrelor-induced bleeding is challenging, as no antidote
is currently available. Platelet transfusion, usually proposed to reverse antiplatelet drugs …

Background Pivotal clinical trials found that ticagrelor reduced ischaemic complications to a
greater extent than clopidogrel, and also that the benefit gradually increased with the …