The interplay between thyroid and liver: implications for clinical practice

E Piantanida, S Ippolito, D Gallo, E Masiello… - Journal of …, 2020 - Springer
A complex relationship exists between thyroid and liver in health and disease. Liver plays an
essential physiological role in thyroid hormone activation and inactivation, transport, and …

Endocrine and liver interaction: the role of endocrine pathways in NASH

P Loria, L Carulli, M Bertolotti, A Lonardo - … reviews Gastroenterology & …, 2009 - nature.com
This article reviews evidence that causally links hormonal disorders with hepatobiliary
disease, and gives particular focus to nonalcoholic steatohepatitis (NASH). The downstream …

Action of thyroid hormones, T3 and T2, on hepatic fatty acids: differences in metabolic effects and molecular mechanisms

F Damiano, A Rochira, A Gnoni, L Siculella - International journal of …, 2017 - mdpi.com
The thyroid hormones (THs) 3, 3′, 5, 5′-tetraiodo-l-thyronine (T4) and 3, 5, 3′-triiodo-l-
thyronine (T3) influence many metabolic pathways. The major physiological function of THs …

[HTML][HTML] Hepatic dysfunction in hyperthyroidism

S Khemichian, TL Fong - Gastroenterology & hepatology, 2011 - ncbi.nlm.nih.gov
Hyperthyroidism can affect multiple organ systems, including the cardiovascular, nervous,
gastrointestinal, and hepatic systems. The interaction between the thyroid and liver is critical …

Early-life exposure to bisphenol a induces liver injury in rats involvement of mitochondria-mediated apoptosis

W Xia, Y Jiang, Y Li, Y Wan, J Liu, Y Ma, Z Mao… - PloS one, 2014 - journals.plos.org
Exposure to bisphenol A (BPA), a monomer widely used to manufacture polycarbonate
plastics, has been reported to be associated with abnormalities of liver function and hepatic …

Abnormal liver blood tests in patients with hyperthyroidism: systematic review and meta-analysis

L Scappaticcio, M Longo, MI Maiorino, V Pernice… - Thyroid, 2021 - liebertpub.com
Background: Abnormal liver blood tests (LBTs) in hyperthyroid patients are not uncommonly
encountered. One major adverse event of antithyroid drug (ATD) therapy is drug-induced …

Hypothyroidism: a possible risk factor for liver cancer in patients with no known underlying cause of liver disease

A Reddy, C Dash, A Leerapun, TA Mettler… - Clinical …, 2007 - Elsevier
Background & Aims: Up to 25% of hepatocellular carcinomas (HCCs) seen in US centers
are of unknown etiology. Animal studies suggest that hypothyroidism can directly cause liver …

Incidence of abnormal liver biochemical tests in hyperthyroidism

TY Lin, AO Shekar, N Li, MW Yeh, S Saab… - Clinical …, 2017 - Wiley Online Library
Objective Abnormal serum liver function tests are common in patients with untreated
thyrotoxicosis, even prior to the initiation of antithyroidal medications that may worsen the …

The thyroid hormone receptor β induces DNA damage and premature senescence

A Zambrano, V García-Carpizo, ME Gallardo… - Journal of Cell …, 2014 - rupress.org
There is increasing evidence that the thyroid hormone (TH) receptors (THRs) can play a role
in aging, cancer and degenerative diseases. In this paper, we demonstrate that binding of …

Thyroid hormones and mortality risk in euthyroid individuals: the Kangbuk Samsung health study

Y Zhang, Y Chang, S Ryu, J Cho… - The Journal of …, 2014 - academic.oup.com
Context: Hyperthyroidism and hypothyroidism, both overt and subclinical, are associated
with all-cause and cardiovascular mortality. The association between thyroid hormones and …