Chalcones and their derivatives have been widely studied due to their versatile
pharmacological and biological activities, such as anti-inflammatory, antibacterial, antiviral …

This study focuses on the development of a machine learning ensemble approach for the
classification of Beta-Secretase 1 (BACE1) inhibitors in Quantitative Structure-Activity …

This comprehensive review explores the pivotal role of ensemble machine learning
techniques in Quantitative Structure-Activity Relationship (QSAR) modeling for drug …

Cancer persists as a significant global health challenge, marked by uncontrolled cell growth
and the potential for metastasis, posing a substantial threat to human well-being. Recent …

We investigate thiazolyl-pyrazoline derivatives as promising drugs for the anti-malarial.
Protein kinase G is a primary target for treating malaria due to its essential role in …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by diverse
symptoms, where accurate diagnosis remains challenging. Traditional clinical observation …

The viral disease dengue is transmitted by the Aedes mosquito and is commonly seen to
occur in the tropical and subtropical regions of the world. It is a growing public health …

Malaria is a disease caused by the Plasmodium falciparum parasite and leads to many
cases of deaths. Recently, the combination of several drugs has been used to treat this …

Predicting acute oral toxicity LD50 of chemicals in rats is a challenge since many factors
affect toxicity data. In this paper, 40 descriptors were successfully used to develop a …

Dengue fever, prevalent in Southeast Asian countries, currently lacks effective
pharmaceutical interventions for virus replication control. This study employs a strategy that …