Diabetes mellitus comprises a group of carbohydrate metabolism disorders that share a
common main feature of chronic hyperglycemia that results from defects of insulin secretion …

Exosomes are small extracellular vesicles 40–160 nm in diameter that are secreted by
almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids …

Kidney tubular cell death induced by transforming growth factor-β1 (TGF-β1) is known to
contribute to diabetic nephropathy, a major complication of diabetes. Caspase-3-dependent …

Significance: Intrarenal oxidative stress plays a critical role in the initiation and progression
of diabetic kidney disease (DKD). Enhanced oxidative stress results from overproduction of …

Various studies, especially in recent years, have shown that quercetin has beneficial
therapeutic effects in various human diseases, including diabetes. Quercetin has significant …

Diabetes prevalence is increasing worldwide, especially through the increase of type 2
diabetes. Diabetic nephropathy occurs in up to 40% of diabetic patients and is the leading …

Several inositol isomers and in particular myo-inositol (MI) and D-chiro-inositol (DCI), were
shown to possess insulin-mimetic properties and to be efficient in lowering post-prandial …

The antidiabetic activity of two low doses of Moringa seed powder (50 and 100 mg/kg body
weight, in the diet) on streptozotocin (STZ) induced diabetes male rats was investigated …

The prevalence of diabetes has dramatically increased worldwide due to the vast increase
in the obesity rate. Diabetic nephropathy is one of the major complications of type 1 and type …

The condition of oxidative stress arises when oxidant production exceeds antioxidant activity
in cells and plasma. The overabundance of oxidants is mechanistically connected to the …