Current development of biodegradable polymeric materials for biomedical applications

R Song, M Murphy, C Li, K Ting, C Soo… - Drug design …, 2018 - Taylor & Francis
In the last half-century, the development of biodegradable polymeric materials for
biomedical applications has advanced significantly. Biodegradable polymeric materials are …

Drug delivery systems and materials for wound healing applications

S Saghazadeh, C Rinoldi, M Schot, SS Kashaf… - Advanced drug delivery …, 2018 - Elsevier
Chronic, non-healing wounds place a significant burden on patients and healthcare
systems, resulting in impaired mobility, limb amputation, or even death. Chronic wounds …

Synthetic biodegradable functional polymers for tissue engineering: a brief review

BL Guo, PX Ma - Science China Chemistry, 2014 - Springer
Scaffolds play a crucial role in tissue engineering. Biodegradable polymers with great
processing flexibility are the predominant scaffolding materials. Synthetic biodegradable …

Evolution of macromolecular complexity in drug delivery systems

A Kakkar, G Traverso, OC Farokhzad… - Nature Reviews …, 2017 - nature.com
Designing therapeutics is a process with many challenges. Even if the first hurdle—
designing a drug that modulates the action of a particular biological target in vitro—is …

Challenges in delivering therapeutic peptides and proteins: A silk-based solution

J Wu, JK Sahoo, Y Li, Q Xu, DL Kaplan - Journal of Controlled Release, 2022 - Elsevier
Peptide-and protein-based therapeutics have drawn significant attention over the past few
decades for the treatment of infectious diseases, genetic disorders, oncology, and many …

Biopolymers; definition, classification and applications

MES Hassan, J Bai, DQ Dou - Egyptian Journal of Chemistry, 2019 - journals.ekb.eg
During recent years significant advances have been made in using and development of
biodegradable polymeric materials for life applications. Degradable polymeric biomaterials …

Prodrug approaches for the development of a long-acting drug delivery systems

ST Chien, IT Suydam, KA Woodrow - Advanced Drug Delivery Reviews, 2023 - Elsevier
Long-acting formulations are designed to reduce dosing frequency and simplify dosing
schedules by providing an extended duration of action. One approach to obtain long-acting …

Polymeric drug delivery systems for localized cancer chemotherapy

R De Souza, P Zahedi, CJ Allen, M Piquette-Miller - Drug delivery, 2010 - Taylor & Francis
Cancer has become one of the most difficult health challenges of our time, accounting for
millions of deaths yearly. Systemic chemotherapy is the most common therapeutic approach; …

A predictive mechanistic model of drug release from surface eroding polymeric nanoparticles

RT Stiepel, ES Pena, SA Ehrenzeller… - Journal of controlled …, 2022 - Elsevier
Effective drug delivery requires ample dosing at the target tissue while minimizing negative
side effects. Drug delivery vehicles such as polymeric nanoparticles (NPs) are often …

Polymeric nanocarriers in targeted drug delivery systems: A review

P Abasian, S Ghanavati, S Rahebi… - Polymers for …, 2020 - Wiley Online Library
Today's medicine mainly relies on conventional means of therapeutics delivery to the human
body, such as tablets, capsules, syrups, and injectable drugs. Utilizing such techniques are …