Mechanical signalling affects multiple biological processes during development and in adult
organisms, including cell fate transitions, cell migration, morphogenesis and immune …

The plasma membrane of eukaryotic cells is not a simple sheet of lipids and proteins but is
differentiated into subdomains with crucial functions. Caveolae, small pits in the plasma …

The plasma membrane allows the cell to sense and adapt to changes in the extracellular
environment by relaying external inputs via intracellular signaling networks. One central …

Understanding how functional lipid domains in live cell membranes are generated has
posed a challenge. Here, we show that transbilayer interactions are necessary for the …

In response to different types and intensities of mechanical force, cells modulate their
physical properties and adapt their plasma membrane (PM). Caveolae are PM nano …

It is well known that lipids are heterogeneously distributed throughout the cell. Most lipid
species are synthesized in the endoplasmic reticulum (ER) and then distributed to different …

Caveolae are abundant surface pits formed by the assembly of cytoplasmic proteins on a
platform generated by caveolin integral membrane proteins and membrane lipids. This …

Caveolae are small, bulb-shaped plasma membrane invaginations. Mutations that ablate
caveolae lead to diverse phenotypes in mice and humans, making it challenging to uncover …

Caveolae are an abundant feature of the plasma membrane in many cells. Until recently,
they were generally considered to be membrane invaginations whose formation primarily …

Plasma membrane depolarization can trigger cell proliferation, but how membrane potential
influences mitogenic signaling is uncertain. Here, we show that plasma membrane …