Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells
B Rehermann - Nature medicine, 2013 - nature.com
Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections account for 57% of
cases of liver cirrhosis and 78% of cases of primary liver cancer worldwide and cause a …
cases of liver cirrhosis and 78% of cases of primary liver cancer worldwide and cause a …
[HTML][HTML] Innate and adaptive immune responses in HCV infections
MH Heim, R Thimme - Journal of hepatology, 2014 - Elsevier
Hepatitis C virus has been identified a quarter of a decade ago as a leading cause of
chronic viral hepatitis that can lead to cirrhosis and hepatocellular carcinoma. Only a …
chronic viral hepatitis that can lead to cirrhosis and hepatocellular carcinoma. Only a …
Direct-acting antiviral prophylaxis in kidney transplantation from hepatitis C virus–infected donors to noninfected recipients: an open-label nonrandomized trial
CM Durand, MG Bowring, DM Brown… - Annals of internal …, 2018 - acpjournals.org
Background: Given the high mortality rate for patients with end-stage kidney disease
receiving dialysis and the efficacy and safety of hepatitis C virus (HCV) treatments …
receiving dialysis and the efficacy and safety of hepatitis C virus (HCV) treatments …
Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection
N Hensel, Z Gu, Sagar, D Wieland, K Jechow… - Nature …, 2021 - nature.com
In chronic hepatitis C virus (HCV) infection, exhausted HCV-specific CD8+ T cells comprise
memory-like and terminally exhausted subsets. However, little is known about the molecular …
memory-like and terminally exhausted subsets. However, little is known about the molecular …
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
Exhausted T cells express multiple co-inhibitory molecules that impair their function and limit
immunity to chronic viral infection. Defining novel markers of exhaustion is important both for …
immunity to chronic viral infection. Defining novel markers of exhaustion is important both for …
[PDF][PDF] Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses
WO Osburn, AE Snider, BL Wells, R Latanich… - …, 2014 - Wiley Online Library
The contribution of humoral immune responses to spontaneous control of hepatitis C virus
(HCV) infection remains unclear. We assessed neutralizing antibody (nAb) responses …
(HCV) infection remains unclear. We assessed neutralizing antibody (nAb) responses …
Spontaneous control of primary hepatitis C virus infection and immunity against persistent reinfection
WO Osburn, BE Fisher, KA Dowd, G Urban, L Liu… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: We followed patients with ongoing hepatitis C virus (HCV)
exposure following control of an initial HCV infection to determine whether primary control …
exposure following control of an initial HCV infection to determine whether primary control …
Acute hepatitis C
A Maheshwari, S Ray, PJ Thuluvath - The Lancet, 2008 - thelancet.com
Symptomatic acute hepatitis C occurs in only about 15% of patients who are infected with
hepatitis C virus (HCV). Acute hepatitis C is most often diagnosed in the setting of post …
hepatitis C virus (HCV). Acute hepatitis C is most often diagnosed in the setting of post …
Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo
T Von Hahn, JC Yoon, H Alter, CM Rice, B Rehermann… - Gastroenterology, 2007 - Elsevier
Background & Aims: Broadly reactive neutralizing antibodies (nAbs) and multispecific T-cell
responses are generated during chronic hepatitis C virus (HCV) infection and yet fail to clear …
responses are generated during chronic hepatitis C virus (HCV) infection and yet fail to clear …