[HTML][HTML] Eosinophil-derived neurotoxin (EDN/RNase 2) and the mouse eosinophil-associated RNases (mEars): expanding roles in promoting host defense

HF Rosenberg - International journal of molecular sciences, 2015 - mdpi.com
The eosinophil-derived neurotoxin (EDN/RNase2) and its divergent orthologs, the mouse
eosinophil-associated RNases (mEars), are prominent secretory proteins of eosinophilic …

Pseudogenes in cancer: state of the art

AK Nakamura-García, J Espinal-Enríquez - Cancers, 2023 - mdpi.com
Simple Summary Out of the billions of nucleotides comprising the human DNA, a substantial
proportion (98%) represents non-coding DNA, meaning DNA that is not translated into …

The Wolbachia endosymbiont as an anti-filarial nematode target

BE Slatko, MJ Taylor, JM Foster - Symbiosis, 2010 - Springer
Human disease caused by parasitic filarial nematodes is a major cause of global morbidity.
The parasites are transmitted by arthropod intermediate hosts and are responsible for …

The life history of retrocopies illuminates the evolution of new mammalian genes

FN Carelli, T Hayakawa, Y Go, H Imai… - Genome …, 2016 - genome.cshlp.org
New genes contribute substantially to adaptive evolutionary innovation, but the functional
evolution of new mammalian genes has been little explored at a broad scale. Previous work …

Evolution and function of developmentally dynamic pseudogenes in mammals

SH Qian, L Chen, YL Xiong, ZX Chen - Genome Biology, 2022 - Springer
Background Pseudogenes are excellent markers for genome evolution, which are emerging
as crucial regulators of development and disease, especially cancer. However, systematic …

Endosymbiont DNA in endobacteria-free filarial nematodes indicates ancient horizontal genetic transfer

SN McNulty, JM Foster, M Mitreva, JC Dunning Hotopp… - PloS one, 2010 - journals.plos.org
Background Wolbachia are among the most abundant symbiotic microbes on earth; they are
present in about 66% of all insect species, some spiders, mites and crustaceans, and most …

Pseudogenes and their genome-wide prediction in plants

J Xiao, MK Sekhwal, P Li, R Ragupathy… - International Journal of …, 2016 - mdpi.com
Pseudogenes are paralogs generated from ancestral functional genes (parents) during
genome evolution, which contain critical defects in their sequences, such as lacking a …

Structural characterization and duplication modes of pseudogenes in plants

F Mascagni, G Usai, A Cavallini, A Porceddu - Scientific Reports, 2021 - nature.com
We identified and characterized the pseudogene complements of five plant species: four
dicots (Arabidopsis thaliana, Vitis vinifera, Populus trichocarpa and Phaseolus vulgaris) and …

Pathological roles of miRNAs and pseudogene-derived lncRNAs in human cancers, and their comparison as prognosis/diagnosis biomarkers

B Karimi, K Mokhtari, H Rozbahani, M Peymani… - … -Research and Practice, 2023 - Elsevier
This review examines and compares the diagnostic and prognostic capabilities of miRNAs
and lncRNAs derived from pseudogenes in cancer patients. Additionally, it delves into their …

Interchromosomal Colocalization with Parental Genes Is Linked to the Function and Evolution of Mammalian Retrocopies

Y Yan, Y Tian, Z Wu, K Zhang… - Molecular Biology and …, 2023 - academic.oup.com
Retrocopies are gene duplicates arising from reverse transcription of mature mRNA
transcripts and their insertion back into the genome. While long being regarded as …