Challenges for the human immune system after leaving Earth

S Marchal, A Choukér, J Bereiter-Hahn, A Kraus… - npj …, 2024 - nature.com
From the start of life on Earth, several immune defense mechanisms have evolved to
guarantee cellular integrity, homeostasis, and host survival. All these sophisticated balances …

Phylogenomics, phenotypic, and functional traits of five novel (Earth-derived) bacterial species isolated from the International Space Station and their prevalence in …

AC Simpson, P Sengupta, F Zhang, A Hameed… - Scientific Reports, 2023 - nature.com
With the advent of long-term human habitation in space and on the moon, understanding
how the built environment microbiome of space habitats differs from Earth habitats, and how …

Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station

C Urbaniak, MD Morrison, JB Thissen, F Karouia… - Microbiome, 2022 - Springer
Abstract Background The International Space Station (ISS) is a unique and complex built
environment with the ISS surface microbiome originating from crew and cargo or from life …

Multidrug-resistant Acinetobacter pittii is adapting to and exhibiting potential succession aboard the International Space Station

BT Tierney, NK Singh, AC Simpson, AM Hujer… - Microbiome, 2022 - Springer
Background Monitoring the adaptation of microorganisms to the extreme environment of the
International Space Station (ISS) is crucial to understanding microbial evolution and …

Challenges and opportunities for bioactive compound and antibiotic discovery in deep space

AC Simpson - Journal of the Indian Institute of Science, 2023 - Springer
Long-term space habitation for exploratory missions or colonization will involve significant
health risks to astronauts living in enclosed habitats in altered gravity, for years at a time with …

Comparative Genomics of Novel Agrobacterium G3 Strains Isolated From the International Space Station and Description of Agrobacterium tomkonis sp. nov.

NK Singh, C Lavire, J Nesme, L Vial, X Nesme… - Frontiers in …, 2021 - frontiersin.org
Strains of Agrobacterium genomospecies 3 (ie, genomovar G3 of the Agrobacterium
tumefaciens species complex) have been previously isolated from diverse environments …

Comparative genomic analysis of Cohnella hashimotonis sp. nov. isolated from the International Space Station

AC Simpson, VVR Eedara, NK Singh… - Frontiers in …, 2023 - frontiersin.org
A single strain from the family Paenibacillaceae was isolated from the wall behind the Waste
Hygiene Compartment aboard the International Space Station (ISS) in April 2018, as part of …

Microbial adaptation to spaceflight is correlated with bacteriophage-encoded functions

I Irby, JT Broddrick - Nature Communications, 2024 - nature.com
Abstract Evidence from the International Space Station suggests microbial populations are
rapidly adapting to the spacecraft environment; however, the mechanism of this adaptation …

[HTML][HTML] Phylogenetic affiliations and genomic characterization of novel bacterial species and their abundance in the International Space Station

AC Simpson, P Sengupta, F Zhang, A Hameed… - Research …, 2023 - ncbi.nlm.nih.gov
Background With the advent of long-term human habitation in space and on the moon,
understanding how the built environment microbiome of space habitats differs from Earth …

Microbial life in space

RS Thombre, K Kaur, SS Jagtap, J Dixit… - New Frontiers in …, 2022 - Elsevier
Outer space is a harsh environment harboring multiple forms of stress like cosmic radiation,
space vacuum, extreme temperature and pressure, UV radiations, and altered gravity …