Molecular diagnostics are revolutionising the clinical practice of infectious disease. Their
effects will be significant in acute-care settings where timely and accurate diagnostic tools …

Background Conventional tests for tuberculous pleuritis have several limitations. A variety of
new, rapid tests such as nucleic acid amplification tests–including polymerase chain …

Definitive and rapid diagnosis of extrapulmonary tuberculosis is challenging since
conventional techniques have limitations. We have developed a universal sample …

Different transmission routes, including the ingestion of undercooked meat, can result in
Toxoplasma gondii infection in humans. The development of effective prevention strategies …

The sensitivities of the Xpert MTB/RIF test and an in-house IS 6110-based real-time PCR
using TaqMan probes (IS 6110-TaqMan assay) for the detection of Mycobacterium …

PCR and other sequence-based microbial detection methods, once considered to be only
research tools, are being used increasingly in the clinical microbiology laboratory. As this …

Molecular analysis of Mycobacterium ulcerans has revealed two new insertion sequences
(ISs), IS 2404 and IS 2606. IS 2404 was identified by complete sequencing of a previously …

In cases of suspected extrapulmonary tuberculosis, rapid and accurate laboratory diagnosis
is of prime importance, since traditional techniques of detecting acid-fast bacilli have …

Urine cell-free DNA (cfDNA) is a valuable noninvasive biomarker for cancer mutation
detection, infectious disease diagnosis (eg, tuberculosis), organ transplantation monitoring …

Background We have evaluated a sensitive screening assay for Mycobacterium tuberculosis
(MTB) complex organisms and a specific assay for detecting Mycobacterium bovis DNA in …