MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …

microRNAs (miRNAs) are small non-coding RNA molecules, evolutionary conserved. They
target more than one mRNAs, thus influencing multiple molecular pathways, but also …

RNA transfer via extracellular vesicles (EVs) influences cell phenotypes; however, lack of
information regarding biogenesis of RNA-containing EVs has limited progress in the field …

Metabolic switch from oxidative phosphorylation to aerobic glycolysis, which is also called
the Warburg effect, is a hallmark of osteosarcoma (OS) and leads to the enhancement of cell …

AGO/miRNA-mediated gene silencing and ubiquitin-mediated protein quality control
represent two fundamental mechanisms that control proper gene expression. Here, we …

Background The low expression of miR93/25 (members of miR-106b~ 25 cluster) promoted
the invasion and metastasis of colon cancer cells, which predicted poor survival. However …

Background Osteosarcoma (OS) is a common primary bone malignancy. Long noncoding
RNA HCG18 is known to play an important role in a variety of cancers. However, its role in …

Different methods have recently been developed to understand the subcellular localization
and role of microRNAs (miRNAs) as well as small RNAs associated with Argonaute (AGO) …

A major challenge to our understanding of translational control has been deconvolving the
individual impact specific regulatory factors have on the complex dynamics of mRNA …

The lncRNA LINC01123 has been reported to act as an oncogene in many human cancers.
Nevertheless, the function and underlying mechanism of LINC01123 in osteosarcoma (OS) …