WA Catterall - Cold Spring Harbor perspectives in …, 2011 - cshperspectives.cshlp.org
Voltage-gated calcium (Ca2+) channels are key transducers of membrane potential changes into intracellular Ca2+ transients that initiate many physiological events. There are …
RS Zucker, WG Regehr - Annual review of physiology, 2002 - annualreviews.org
▪ Abstract Synaptic transmission is a dynamic process. Postsynaptic responses wax and wane as presynaptic activity evolves. This prominent characteristic of chemical synaptic …
WJ Gehring, AR Willoughby - Science, 2002 - science.org
We report the observation of neural processing that occurs within 265 milliseconds after outcome stimuli that inform human participants about gains and losses in a gambling task. A …
WG Regehr - Cold Spring Harbor perspectives in biology, 2012 - cshperspectives.cshlp.org
Different types of synapses are specialized to interpret spike trains in their own way by virtue of the complement of short-term synaptic plasticity mechanisms they possess. Numerous …
The intracellular calcium concentration ([Ca 2+]) has important roles in the triggering of neurotransmitter release and the regulation of short-term plasticity (STP). Transmitter …
Voltage-gated calcium (Ca 2+) channels initiate release of neurotransmitters at synapses, and regulation of presynaptic Ca 2+ channels has a powerful influence on synaptic strength …
D Fioravante, WG Regehr - Current opinion in neurobiology, 2011 - Elsevier
Synapses exhibit several forms of short-term plasticity that play a multitude of computational roles. Short-term depression suppresses neurotransmitter release for hundreds of …
The size of a pool of readily releasable vesicles at a giant brainstem synapse, the calyx of Held, was probed with three independent approaches. Using simultaneous pre-and …
Abstract Analysis of presynaptic determinants of synaptic strength has been difficult at cortical synapses, mainly due to the lack of direct access to presynaptic elements. Here we …