Environmental chemical exposures and autism spectrum disorders: a review of the epidemiological evidence

AE Kalkbrenner, RJ Schmidt, AC Penlesky - Current problems in pediatric …, 2014 - Elsevier
In the past decade, the number of epidemiological publications addressing environmental
chemical exposures and autism has grown tremendously. These studies are important …

[HTML][HTML] Biospecimens and the ABCD study: Rationale, methods of collection, measurement and early data

KA Uban, MK Horton, J Jacobus, C Heyser… - Developmental cognitive …, 2018 - Elsevier
Biospecimen collection in the Adolescent Brain Cognitive Development (ABCD) study–of
hair samples, shed deciduous (baby) teeth, and body fluids–will serve dual functions of …

Can cross-sectional studies contribute to causal inference? It depends

DA Savitz, GA Wellenius - American journal of epidemiology, 2023 - academic.oup.com
Cross-sectional studies—often defined as those in which exposure and outcome are
assessed at the same point in time—are frequently viewed as minimally informative for …

The NIH ECHO Program: investigating how early environmental influences affect child health

CJ Blaisdell, C Park, M Hanspal, M Roary… - Pediatric …, 2022 - nature.com
In September 2016, the National Institutes of Health (NIH) launched a 7-year extramural
research program, Environmental influences on Child Health Outcomes (ECHO; https://echo …

Fetal and postnatal metal dysregulation in autism

M Arora, A Reichenberg, C Willfors, C Austin… - Nature …, 2017 - nature.com
Genetic and environmental factors contribute to the etiologies of autism spectrum disorder
(ASD), but evidence of specific environmental exposures and susceptibility windows is …

Elucidating the links between endocrine disruptors and neurodevelopment

TT Schug, AM Blawas, K Gray, JJ Heindel… - …, 2015 - academic.oup.com
Recent data indicate that approximately 12% of children in the United States are affected by
neurodevelopmental disorders, including attention deficit hyperactivity disorder, learning …

[HTML][HTML] Dentine biomarkers of prenatal and early childhood exposure to manganese, zinc and lead and childhood behavior

MK Horton, L Hsu, BC Henn, A Margolis, C Austin… - Environment …, 2018 - Elsevier
Background Metal exposure alters neurodevelopmental outcomes; little is known about
critical windows of susceptibility when exposure exerts the strongest effect. Objective To …

[HTML][HTML] Prenatal and early childhood critical windows for the association of nephrotoxic metal and metalloid mixtures with kidney function

AP Sanders, C Gennings, M Tamayo-Ortiz… - Environment …, 2022 - Elsevier
Introduction As renal development and maturation processes begin in utero and continue
through early childhood, sensitive developmental periods arise during which metal …

An overview of the current progress, challenges, and prospects of human biomonitoring and exposome studies

MZ Bocato, JP Bianchi Ximenez… - Journal of Toxicology …, 2019 - Taylor & Francis
Human Biomonitoring (HB), the process for determining whether and to what extent
chemical substances penetrated our bodies, serves as a useful tool to quantify human …

Is early-life iron exposure critical in neurodegeneration?

DJ Hare, M Arora, NL Jenkins, DI Finkelstein… - Nature Reviews …, 2015 - nature.com
The effects of iron deficiency are well documented, but relatively little is known about the
long-term implications of iron overload during development. High levels of redox-active iron …