Emerging evidence now indicates that mitochondria are central regulators of neural stem
cell (NSC) fate decisions and are crucial for both neurodevelopment and adult …

Neurodegenerative disorders affect around one billion people worldwide. They can arise
from a combination of genomic, epigenomic, metabolic, and environmental factors. Aging is …

Abstract Alzheimer's disease (AD), the most frequent cause of dementia, is escalating as a
global epidemic, and so far, there is neither cure nor treatment to alter its progression. The …

Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …

Metformin as a first-line drug for type 2 diabetes mellitus (T2DM) treatment is widely studied.
Metformin can reduce liver glucose output and improve insulin resistance. Recent evidence …

Objective: To determine whether metformin is associated with a lower incidence of dementia
than sulfonylureas. Methods: This was a retrospective cohort study of US veterans≥ 65 …

Background Rosmarinus officinalis, commonly known as rosemary, is a medicinal herb that
presents significant biological properties such as antimicrobial, antioxidant, anti …

Aging is a risk factor for major central nervous system (CNS) disorders. More specifically,
aging can be inked to neurodegenerative diseases (NDs) because of its deteriorating impact …

Metformin is a first-line drug for treating type 2 diabetes mellitus (T2DM) and one of the most
commonly prescribed drugs in the world. Besides its hypoglycemic effects, metformin also …

Cancer is one of the most common causes of death; in parallel, the incidence and
prevalence of central nervous system diseases are equally high. Among neurodegenerative …