Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance
High producing dairy cows generally receive in the diet up to 5–6% of fat. This is a relatively
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …
[HTML][HTML] The connexin 43 C-terminus: A tail of many tales
Connexins are chordate gap junction channel proteins that, by enabling direct
communication between the cytosols of adjacent cells, create a unique cell signalling …
communication between the cytosols of adjacent cells, create a unique cell signalling …
Endothelial cell CD36 regulates membrane ceramide formation, exosome fatty acid transfer and circulating fatty acid levels
Endothelial cell (EC) CD36 controls tissue fatty acid (FA) uptake. Here we examine how ECs
transfer FAs. FA interaction with apical membrane CD36 induces Src phosphorylation of …
transfer FAs. FA interaction with apical membrane CD36 induces Src phosphorylation of …
Lemon‐Derived Extracellular Vesicles Nanodrugs Enable to Efficiently Overcome Cancer Multidrug Resistance by Endocytosis‐Triggered Energy Dissipation and …
Q Xiao, W Zhao, C Wu, X Wang, J Chen… - Advanced …, 2022 - Wiley Online Library
Multidrug resistance remains a great challenge for cancer chemotherapy. Herein, a
biomimetic drug delivery system based on lemon‐derived extracellular vesicles (EVs) …
biomimetic drug delivery system based on lemon‐derived extracellular vesicles (EVs) …
N6-methyladenosine demethylase FTO promotes growth and metastasis of gastric cancer via m6A modification of caveolin-1 and metabolic regulation of …
Gastric cancer (GC) is the fifth most common tumor and the third most deadly cancer
worldwide. N6-methyladenosine (m6A) modification has been reported to play a regulatory …
worldwide. N6-methyladenosine (m6A) modification has been reported to play a regulatory …
Substrate Stiffness-Driven Membrane Tension Modulates Vesicular Trafficking via Caveolin-1
Liver fibrosis, a condition characterized by extensive deposition and cross-linking of
extracellular matrix (ECM) proteins, is idiosyncratic in cases of chronic liver injury. The …
extracellular matrix (ECM) proteins, is idiosyncratic in cases of chronic liver injury. The …
Free fatty acids as modulators of the NLRP3 inflammasome in obesity/type 2 diabetes
S Legrand-Poels, N Esser, L L'homme… - Biochemical …, 2014 - Elsevier
Free fatty acids (FFAs) are metabolic intermediates that may be obtained through the diet or
synthesized endogenously. In addition to serving as an important source of energy, they …
synthesized endogenously. In addition to serving as an important source of energy, they …
Strategies for delivering nanoparticles across tumor blood vessels
Nanoparticle transport across tumor blood vessels is a key step in nanoparticle delivery to
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …
Cardiac connexin-43 hemichannels and pannexin1 channels: Provocative antiarrhythmic targets
K Andelova, T Egan Benova… - International Journal of …, 2020 - mdpi.com
Cardiac connexin-43 (Cx43) creates gap junction channels (GJCs) at intercellular contacts
and hemi-channels (HCs) at the peri-junctional plasma membrane and sarcolemmal …
and hemi-channels (HCs) at the peri-junctional plasma membrane and sarcolemmal …
Mid-old cells are a potential target for anti-aging interventions in the elderly
The biological process of aging is thought to result in part from accumulation of senescent
cells in organs. However, the present study identified a subset of fibroblasts and smooth …
cells in organs. However, the present study identified a subset of fibroblasts and smooth …