Fibrosis is defined as an excessive deposition of connective tissue components and can
affect virtually every organ system, including the skin, lungs, liver and kidney. Fibrotic tissue …

Tumor-promoting inflammation and the avoidance of immune destruction are hallmarks of
cancer. While innate immune cells, such as neutrophils, monocytes, and macrophages, are …

As an essential innate immune population for maintaining body homeostasis and warding
off foreign pathogens, macrophages display high plasticity and perform diverse supportive …

The oligonucleotide therapeutics field has seen remarkable progress over the last few years
with the approval of the first antisense drug and with promising developments in late stage …

Distinct anti-inflammatory macrophage (M2) subtypes, namely M2a and M2c, are reported to
modulate the tissue repair process tightly and chronologically by modulating fibroblast …

Despite its polyanionic nature, DNA can cross the negatively charged membrane to enter
living cells by assembling into specific nanostructures, establishing various opportunities for …

Heat shock proteins (HSPs) of eukaryotes are evolutionarily conserved molecules present in
all the major intracellular organelles. They mainly function as molecular chaperones and …

Background With continuous progress over the past few decades in understanding
diagnosis, treatment, and genetics, much has been learned about the prostate cancer …

The vegetative insecticidal proteins (Vip), secreted by many Bacillus thuringiensis strains
during their vegetative growth stage, are genetically distinct from known insecticidal crystal …

Background M2 macrophages play an important role in gastric cancer progression and
metastasis, but the underlying tumor-promoting mechanisms are largely unknown. Methods …