RNase L amplifies interferon signaling by inducing protein kinase R-mediated antiviral stress granules
Virus infection leads to activation of the interferon (IFN)-induced endoribonuclease RNase L,
which results in degradation of viral and cellular RNAs. Both cellular and viral RNA cleavage …
which results in degradation of viral and cellular RNAs. Both cellular and viral RNA cleavage …
Generation of cytotoxic T cells and dysfunctional CD8 T cells in severe COVID-19 patients
SC Gozzi-Silva, LM Oliveira, RW Alberca, NZ Pereira… - Cells, 2022 - mdpi.com
COVID-19, the infectious disease caused by SARS-CoV-2, has spread on a pandemic scale.
The viral infection can evolve asymptomatically or can generate severe symptoms …
The viral infection can evolve asymptomatically or can generate severe symptoms …
Distinct domain organization and diversity of 2′-5′-oligoadenylate synthetases
A Koul, LT Hui, N Lubna… - Biochemistry and Cell …, 2024 - cdnsciencepub.com
The 2′-5′-oligoadenylate synthetases (OAS) are important components of the innate
immune system that recognize viral double-stranded RNA (dsRNA). Upon dsRNA binding …
immune system that recognize viral double-stranded RNA (dsRNA). Upon dsRNA binding …
Molecular mechanism of quorum sensing inhibition in Streptococcus by the phage protein paratox
NR Rutbeek, H Rezasoltani, TR Patel… - Journal of Biological …, 2021 - ASBMB
Streptococcus pyogenes, or Group A Streptococcus, is a Gram-positive bacterium that can
be both a human commensal and a pathogen. Central to this dichotomy are temperate …
be both a human commensal and a pathogen. Central to this dichotomy are temperate …
[PDF][PDF] Initial characterization of the functional cycle of YihA
D Capatos - 2023 - opus.uleth.ca
INITIAL CHARACTERIZATION OF THE FUNCTIONAL CYCLE OF YIHA DORA CAPATOS
Master of Science, University of Alberta, 2013 A thesis su Page 1 INITIAL …
Master of Science, University of Alberta, 2013 A thesis su Page 1 INITIAL …
Mathematical modelling of OAS2 activation by dsRNA and effects of dsRNA lengths
D Lee - 2020 - mspace.lib.umanitoba.ca
Abstract The activation of 2'-5'-oligoadenylate synthetase (OAS) enzymes by direct
interaction with viral double-stranded RNA (dsRNA) is a key part of the innate immune …
interaction with viral double-stranded RNA (dsRNA) is a key part of the innate immune …
Sensores de ARN de cadena doble en la inmunidad innata
B García Japón - 2021 - idus.us.es
La inmunidad innata es uno de los mecanismos principales en la defensa contra la
infección viral. La detección de dsARN viral es uno de los instrumentos que tenemos para …
infección viral. La detección de dsARN viral es uno de los instrumentos que tenemos para …