Membranous nephropathy: new pathogenic mechanisms and their clinical implications

E Hoxha, L Reinhard, RAK Stahl - Nature Reviews Nephrology, 2022 - nature.com
Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …

Membranous nephropathy

P Ronco, L Beck, H Debiec, FC Fervenza… - Nature reviews Disease …, 2021 - nature.com
Membranous nephropathy (MN) is a glomerular disease that can occur at all ages. In adults,
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …

[HTML][HTML] Membranous nephropathy

M Dantas, LBB Silva, BTM Pontes… - Brazilian Journal of …, 2023 - SciELO Brasil
Membranous nephropathy is a glomerulopathy, which main affected target is the podocyte,
and has consequences on the glomerular basement membrane. It is more common in …

Helper T cells in idiopathic membranous nephropathy

Q Zhao, H Dai, X Liu, H Jiang, W Liu, Z Feng… - Frontiers in …, 2021 - frontiersin.org
Idiopathic membranous nephropathy (IMN) is an autoimmune disease in which the immune
system produces an antibody response to its own antigens due to impaired immune …

SARS-CoV2 infection induce miR-155 expression and skewed Th17/Treg balance by changing SOCS1 level: A clinical study

MS Soltani-Zangbar, M Hajivalili, D Daneshdoust… - Cytokine, 2023 - Elsevier
Background One of the regulators in severe acute respiratory syndrome coronavirus2
(SARS-CoV2) infection is miRNAs. In COVID-19 patients, immunological responses to …

[HTML][HTML] Research advances on targeted-Treg therapies on immune-mediated kidney diseases

Y Li, H Liu, H Yan, J Xiong - Autoimmunity Reviews, 2023 - Elsevier
The primary function of regulatory T cells (Tregs) is blocking the pathogenic immunological
response mediated by autoreactive cells, establishing and maintaining immune …

Mesenchymal stem cell protects injured renal tubular epithelial cells by regulating mTOR-mediated Th17/Treg axis

Y Luo, J Guo, P Zhang, YC Cheuk, Y Jiang… - Frontiers in …, 2021 - frontiersin.org
The increase in T helper 17 cell (Th17)-mediated pro-inflammatory response and decrease
in regulatory T cell (Treg)-mediated anti-inflammatory effect aggravate renal tubular …

Identification of biomarkers related to immune and inflammation in membranous nephropathy: comprehensive bioinformatic analysis and validation

P Zhang, Y Geng, J Tang, Z Cao, X Xiang… - Frontiers in …, 2023 - frontiersin.org
Background Membranous nephropathy (MN) is an autoimmune glomerular disease that is
predominantly mediated by immune complex deposition and complement activation. The …

Cytokines network in primary membranous nephropathy

Q Zhao, H Dai, Y Hu, H Jiang, Z Feng, W Liu… - International …, 2022 - Elsevier
There have been extensive studies on the immunological mechanism of primary
membranous nephropathy (PMN). Autoantibodies, being the end product of humoral auto …

Novel biomarkers in membranous nephropathy

Q Liu, J Liu, B Lin, Y Zhang, M Ma, M Yang… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is the main cause of adult nephrotic syndrome (NS). The
pathogenesis of MN is complex and involves subepithelial immune complex deposition …