[HTML][HTML] Pathophysiology of atherosclerosis

S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Mitochondrial proton leak plays a critical role in pathogenesis of cardiovascular diseases

J Cheng, G Nanayakkara, Y Shao, R Cueto… - Mitochondrial Dynamics …, 2017 - Springer
Mitochondrial proton leak is the principal mechanism that incompletely couples substrate
oxygen to ATP generation. This chapter briefly addresses the recent progress made in …

[HTML][HTML] Pathophysiology of acute coronary syndromes—diagnostic and treatment considerations

P Theofilis, E Oikonomou, C Chasikidis, K Tsioufis… - Life, 2023 - mdpi.com
Coronary artery disease and acute coronary syndromes are accountable for significant
morbidity and mortality, despite the preventive measures and technological advancements …

Malnutrition in acute heart failure with preserved ejection fraction: clinical correlates and prognostic implications

SC Chien, CI Lo, CF Lin, KT Sung, JP Tsai… - ESC heart …, 2019 - Wiley Online Library
Aims This study aimed to evaluate the prognostic significance of nutritional status in post‐
discharge Asians with heart failure with preserved ejection fraction (HFpEF). Methods and …

[HTML][HTML] Sex-specific predictors of PCSK9 levels in a European population: The IMPROVE study

N Ferri, M Ruscica, D Coggi, A Bonomi, M Amato… - Atherosclerosis, 2020 - Elsevier
Background and aims Proprotein convertase subtilisin/kexin type 9 (PCSK9) is one of the
key regulators of low-density lipoprotein cholesterol plasma levels. Circulating PCSK9 …

Pathophysiology and targeted treatment of cholesterol crystal embolism and the related thrombotic angiopathy

C Shi, E Mammadova‐Bach, C Li… - The FASEB …, 2023 - epub.ub.uni-muenchen.de
Cholesterol crystal (CC) embolism is a complication of advanced atherosclerotic plaques
located in the major arteries. This pathological condition is primarily induced by …

[HTML][HTML] Microbiota-derived trimethylamine N-oxide predicts cardiovascular risk after STEMI

Y Matsuzawa, H Nakahashi, M Konishi, R Sato… - Scientific Reports, 2019 - nature.com
Abstract Trimethylamine N-oxide (TMAO), a metabolite derived from the gut microbiota, is
proatherogenic and associated with cardiovascular events. However, the change in TMAO …

[HTML][HTML] We are what we eat: impact of food from short supply chain on metabolic syndrome

G Santulli, V Pascale, R Finelli, V Visco… - Journal of clinical …, 2019 - mdpi.com
Food supply in the Mediterranean area has been recently modified by big retail distribution;
for instance, industrial retail has favored shipments of groceries from regions that are …

Mechanisms behind the atherothrombotic effects of acrolein, a review

MR Zirak, S Mehri, A Karimani, M Zeinali… - Food and Chemical …, 2019 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of death worldwide. The majority of
cardiovascular complications are secondary to atherosclerosis. Extensive evidence has …

[HTML][HTML] Targeting inflammation in atherosclerosis: overview, strategy and directions

R Waksman, I Merdler, BC Case… - …, 2024 - eurointervention.pcronline.com
Atherosclerosis is a chronic condition characterised by the build-up of plaque in the inner
lining of the blood vessels and it is the main underlying cause of cardiovascular disease …