The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis

N Gomez-Lopez, J Galaz, D Miller… - …, 2022 - rep.bioscientifica.com
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

Improving pregnancy outcomes in humans through studies in sheep

JL Morrison, MJ Berry, KJ Botting… - American Journal …, 2018 - journals.physiology.org
Experimental studies that are relevant to human pregnancy rely on the selection of
appropriate animal models as an important element in experimental design. Consideration …

Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes

R Romero, J Miranda, P Chaemsaithong… - The journal of …, 2015 - Taylor & Francis
Objective: The objectives of this study were to:(1) determine the amniotic fluid (AF)
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …

Preterm birth, intrauterine infection, and fetal inflammation

MW Kemp - Frontiers in immunology, 2014 - frontiersin.org
Preterm birth (PTB)(delivery before 37 weeks' gestation) is a leading cause of neonatal
death and disease in industrialized and developing countries alike. Infection (most notably …

A novel molecular microbiologic technique for the rapid diagnosis of microbial invasion of the amniotic cavity and intra‐amniotic infection in preterm labor with intact …

R Romero, J Miranda… - American journal of …, 2014 - Wiley Online Library
Problem The diagnosis of microbial invasion of the amniotic cavity (MIAC) has been
traditionally performed using traditional cultivation techniques, which require growth of …

Mechanisms of ventilator-induced lung injury in premature infants

MA Attar, SM Donn - Seminars in Neonatology, 2002 - Elsevier
Mechanical ventilation in premature infants may injure the lungs or exacerbate the pre-
existing condition that led to the need for mechanical ventilation. Ventilator-induced lung …

Prenatal inflammation and lung development

BW Kramer, S Kallapur, J Newnham… - Seminars in fetal and …, 2009 - Elsevier
Prenatal exposure of very low birth weight infants to chronic indolent chorioamnionitis with
organisms such as mycoplasma and ureaplasma is frequent. Chorioamnionitis is …

Chorioamnionitis: a multiorgan disease of the fetus?

M Gantert, JV Been, AWD Gavilanes, Y Garnier… - Journal of …, 2010 - nature.com
The bacterial infection of chorion and amnion is a common finding in premature delivery and
is referred to as chorioamnionitis. As the mother rarely shows symptoms of a systemic …

Fetal immune response to chorioamnionitis

SG Kallapur, P Presicce, CM Rueda… - Seminars in …, 2014 - thieme-connect.com
Chorioamnionitis is a frequent cause of preterm birth and is associated with an increased
risk for injury responses in the lung, gastrointestinal tract, brain, and other fetal organs …

Antenatal factors and the development of bronchopulmonary dysplasia

AH Jobe - Seminars in neonatology, 2003 - Elsevier
The lung of the preterm fetus is often exposed to antenatal glucocorticoids, and histologic
chorioamnionitis is frequent. Clinically and experimentally, antenatal glucocorticoids and/or …