Although some tumor has become a curable disease for many patients, involvement of the
central nervous system (CNS) is still a major concern. The blood–brain barrier (BBB), a …

Brain organoids are 3D cytoarchitectures resembling the embryonic human brain. This
review focuses on current advancements in biomedical engineering methods to develop …

The complex structure of the blood–brain barrier (BBB), which blocks nearly all large
biomolecules, hinders drug delivery to the brain and drug assessment, thus decelerating …

The pharmaceutical industry has entered an era of transformation with the emergence of
Pharma 4.0, which leverages cutting-edge technologies in manufacturing processes. These …

The present study focused on the hypoglycemic, anti-inflammatory and anti-aging effects of
Canthium coromandelicum (Burm. f.) Alston leaf extract by in vitro and in silico analyses. In …

Plethora of research has shed light on the critical role of synaptic dysfunction in various
neurodegenerative disorders (NDDs), including Alzheimer's disease (AD), Parkinson's …

The advent of stem cell-derived cerebral organoids has already advanced our
understanding of disease mechanisms in neurological diseases. Despite this, many remain …

Advanced brain organoids provide promising platforms for deciphering the cellular and
molecular processes of human neural development and diseases. Although various studies …

Anisotropically organized neural networks are indispensable routes for functional
connectivity in the brain, which remains largely unknown. While prevailing animal models …

Neurodegenerative diseases (NDs) are severe disorders of the nervous system, and their
causes are still not completely understood. Modeling the complex pathological mechanisms …