Most cancer biologists still rely on conventional two-dimensional (2D) monolayer culture
techniques to test in vitro anti-tumor drugs prior to in vivo testing. However, the vast majority …

Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …

Simple Summary Three-dimensional (3D) cell culture models have been proposed as
alternatives for initial drug screening to increase drug development efficiency. In addition to …

The therapeutic efficacy of drugs is dependent upon the ability of a drug to reach its target,
and drug penetration into tumors is limited by abnormal vasculature and high interstitial …

Nanocarriers have been widely employed in preclinical studies and clinical trials for the
delivery of anticancer drugs. The most important causes of failure in clinical translation of …

The interface of bio–nano science and cancer medicine is an area experiencing much
progress but also beset with controversy. Core concepts of the field eg, the enhanced …

It is well known that most particle technology studies attempting to predict secondary
properties based on primary properties such as size and shape begin with particle …

Bioactive compounds (eg, flavonoids, phenolics acids, alkaloids and carotenoids) are
commercially-valued products, due to their wide array of applications in the medical …

Tumor penetration is important for effectively tumor targeting drug delivery. Recently, many
researches are published to overcome the barriers that restrict tumor penetration and …

Human struggle against the deadly disease conditions is continued since ages. The
contribution of science and technology in fighting against these diseases cannot be ignored …