Review of advances in electrospinning-based strategies for spinal cord regeneration

Y Li, T Dong, Z Li, S Ni, F Zhou, OA Alimi, S Chen… - Materials Today …, 2022 - Elsevier
Spinal cord injury (SCI) is a devastating neurological condition, commonly leading to
physical and mental deficiencies, pain, other complications, and even death. Most recently …

[HTML][HTML] Molecular insights into the pathogenic impact of vitamin D deficiency in neurological disorders

MJ Anwar, SK Alenezi, AH Alhowail - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Neurological disorders are the major cause of disability, leading to a decrease in quality of
life by impairing cognitive, sensorimotor, and motor functioning. Several factors have been …

[HTML][HTML] A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury

Z Li, T Zhao, J Ding, H Gu, Q Wang, Y Wang, D Zhang… - Bioactive materials, 2023 - Elsevier
Spinal cord injury (SCI) is an overwhelming and incurable disabling event accompanied by
complicated inflammation-related pathological processes, such as excessive reactive …

Heterogeneity analysis of astrocytes following spinal cord injury at single‐cell resolution

J Hou, H Bi, Q Ge, H Teng, G Wan, B Yu… - The FASEB …, 2022 - Wiley Online Library
Astrocytes play many important functions in response to spinal cord injury (SCI) in an
activated manner, including clearance of necrotic tissue, formation of protective barrier …

Reactive astrocytes in central nervous system injury: subgroup and potential therapy

GL Yu, Y Zhang, B Ning - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Traumatic central nervous system (CNS) injury, which includes both traumatic brain injury
(TBI) and spinal cord injury (SCI), is associated with irreversible loss of neurological function …

Effects of astrocytes and microglia on neuroinflammation after spinal cord injury and related immunomodulatory strategies

QM Pang, SY Chen, QJ Xu, M Zhang, DF Liang… - International …, 2022 - Elsevier
Spinal cord injury (SCI) is a catastrophic event which is still without adequate therapies.
Neuroinflammation is the main pathogenesis of secondary damage post-SCI, leading to …

Photobiomodulation promotes repair following spinal cord injury by regulating the transformation of A1/A2 reactive astrocytes

X Wang, Z Zhang, Z Zhu, Z Liang, X Zuo, C Ju… - Frontiers in …, 2021 - frontiersin.org
After spinal cord injury (SCI), reactive astrocytes can be classified into two distinctive
phenotypes according to their different functions: neurotoxic (A1) astrocytes and …

Function Follows Form: Oriented Substrate Nanotopography Overrides Neurite-Repulsive Schwann Cell–Astrocyte Barrier Formation in an In Vitro Model of Glial …

P Achenbach, L Hillerbrand, JL Gerardo-Nava… - Nano Letters, 2023 - ACS Publications
Schwann cell (SC) transplantation represents a promising therapeutic approach for
traumatic spinal cord injury but is frustrated by barrier formation, preventing cell migration …

Electrospun fiber scaffolds for engineering glial cell behavior to promote neural regeneration

DL Puhl, JL Funnell, DW Nelson, MK Gottipati… - Bioengineering, 2020 - mdpi.com
Electrospinning is a fabrication technique used to produce nano-or micro-diameter fibers to
generate biocompatible, biodegradable scaffolds for tissue engineering applications …

Astrocyte polarization in glaucoma: a new opportunity

YX Liu, H Sun, WY Guo - Neural regeneration research, 2022 - journals.lww.com
Astrocyte polarization is a new concept which is similar to microglia polarization and in
which astrocytes are classified as A1 (neurotoxic) and A2 (neuroprotective). Several studies …