Deuterium metabolic imaging (DMI) is an emerging clinically-applicable technique for the
non-invasive investigation of tissue metabolism. The generally short T 1 values of 2 H …

Hyperpolarized carbon 13 MRI (13C MRI) is a novel imaging approach that can
noninvasively probe tissue metabolism in both normal and pathologic tissues. The process …

Objectives Noninvasive, affordable, and reliable mapping of brain glucose metabolism is of
critical interest for clinical research and routine application as metabolic impairment is linked …

Background Impaired glucose metabolism is characteristic of several types of dementia,
preceding cognitive symptoms and structural brain changes. Reduced glucose uptake in …

Introduction There is a lack of robust metabolic imaging techniques that can be routinely
applied to characterize lesions in patients with brain tumors. Here we explore in an animal …

Introduction Deuterium metabolic imaging (DMI) and quantitative exchange label turnover
(QELT) are novel MR spectroscopy techniques for non-invasive imaging of human brain …

Abstract MRI with hyperpolarized (HP) 13C agents, also known as HP 13C MRI, can
measure processes such as localized metabolism that is altered in numerous cancers, liver …

Purpose To explore the potential of deuterium metabolic imaging (DMI) in the human brain
in vivo at 7 T, using a multi‐element deuterium (2H) RF coil for 3D volume coverage …

Aberrations in metabolism after intracerebral hemorrhage (ICH), particularly lactate
metabolism, play a crucial role in the pathophysiology and patient outcome. To date, the …

Objective: Information on the metabolism of tissues in healthy and diseased states plays a
significant role in the detection and understanding of tumors, neurodegenerative diseases …