COVID‐19: Virology, biology and novel laboratory diagnosis
Background At the end of December 2019, a novel coronavirus tentatively named SARS‐
CoV‐2 in Wuhan, a central city in China, was announced by the World Health Organization …
CoV‐2 in Wuhan, a central city in China, was announced by the World Health Organization …
[HTML][HTML] Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions
COVID-19 is a worldwide pandemic caused by SARS-coronavirus-2 (SARS-CoV-2). Less
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …
The COVID-19 pandemic: a comprehensive review of taxonomy, genetics, epidemiology, diagnosis, treatment, and control
A pneumonia outbreak with unknown etiology was reported in Wuhan, Hubei province,
China, in December 2019, associated with the Huanan Seafood Wholesale Market. The …
China, in December 2019, associated with the Huanan Seafood Wholesale Market. The …
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
J Wenzel, J Lampe, H Müller-Fielitz, R Schuster… - Nature …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) can damage cerebral small vessels and
cause neurological symptoms. Here we describe structural changes in cerebral small …
cause neurological symptoms. Here we describe structural changes in cerebral small …
X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the pathogen
that causes COVID-19, produces polyproteins 1a and 1ab that contain, respectively, 11 or …
that causes COVID-19, produces polyproteins 1a and 1ab that contain, respectively, 11 or …
SARS‐CoV‐2 infection, COVID‐19 pathogenesis, and exposure to air pollution: What is the connection?
B Woodby, MM Arnold… - Annals of the new York …, 2021 - Wiley Online Library
Exposure to air pollutants has been previously associated with respiratory viral infections,
including influenza, measles, mumps, rhinovirus, and respiratory syncytial virus …
including influenza, measles, mumps, rhinovirus, and respiratory syncytial virus …
SARS coronavirus 2: from genome to infectome
M Rastogi, N Pandey, A Shukla, SK Singh - Respiratory research, 2020 - Springer
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) belongs to the group of
Betacoronaviruses. The SARS-CoV-2 is closely related to SARS-CoV-1 and probably …
Betacoronaviruses. The SARS-CoV-2 is closely related to SARS-CoV-1 and probably …
A Comparative Analysis of SARS-CoV-2 Antivirals Characterizes 3CLpro Inhibitor PF-00835231 as a Potential New Treatment for COVID-19
M de Vries, AS Mohamed, RA Prescott… - Journal of …, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
coronavirus disease 2019 (COVID-19). There is a dire need for novel effective antivirals to …
coronavirus disease 2019 (COVID-19). There is a dire need for novel effective antivirals to …
SARS-CoV-2: Targeted managements and vaccine development
Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) results in
diverse outcomes. The symptoms appear to be more severe in males older than 65 and …
diverse outcomes. The symptoms appear to be more severe in males older than 65 and …
Targeting novel structural and functional features of coronavirus protease nsp5 (3CLpro, Mpro) in the age of COVID-19
MK Roe, NA Junod, AR Young… - Journal of General …, 2021 - microbiologyresearch.org
Coronavirus protease nsp5 (M pro, 3CL pro) remains a primary target for coronavirus
therapeutics due to its indispensable and conserved role in the proteolytic processing of the …
therapeutics due to its indispensable and conserved role in the proteolytic processing of the …