Microbiota and maintenance of skin barrier function

TA Harris-Tryon, EA Grice - Science, 2022 - science.org
Human skin forms a protective barrier against the external environment and is our first line of
defense against toxic, solar, and pathogenic insults. Our skin also defines our outward …

Next-generation sequencing: insights to advance clinical investigations of the microbiome

CR Wensel, JL Pluznick, SL Salzberg… - The Journal of clinical …, 2022 - Am Soc Clin Investig
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …

Skin barrier function and the microbiome

HJ Lee, M Kim - International journal of molecular sciences, 2022 - mdpi.com
Human skin is the largest organ and serves as the first line of defense against environmental
factors. The human microbiota is defined as the total microbial community that coexists in the …

The skin microbiome: current landscape and future opportunities

P Smythe, HN Wilkinson - International journal of molecular sciences, 2023 - mdpi.com
Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …

One population, multiple lifestyles: commensalism and pathogenesis in the human mycobiome

DM Proctor, RA Drummond, MS Lionakis, JA Segre - Cell host & microbe, 2023 - cell.com
Candida auris and Candida albicans can result in invasive fungal diseases. And yet, these
species can stably and asymptomatically colonize human skin and gastrointestinal tracts. To …

Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis

L Chi, C Liu, I Gribonika, J Gschwend, D Corral, SJ Han… - Science, 2024 - science.org
Males and females exhibit profound differences in immune responses and disease
susceptibility. However, the factors responsible for sex differences in tissue immunity remain …

[HTML][HTML] Forgotten fungi: the importance of the skin mycobiome

UT Nguyen, LR Kalan - Current opinion in microbiology, 2022 - Elsevier
Highlights•The fungal mycobiome on the skin is shaped by skin physiology and
age.•Disruption of fungal–bacterial network is associated with dermatological …

[HTML][HTML] Skin barrier immunology from early life to adulthood

A Trompette, ND Ubags - Mucosal Immunology, 2023 - Elsevier
Our skin has a unique barrier function, which is imperative for the body's protection against
external pathogens and environmental insults. Although interacting closely and sharing …

[HTML][HTML] Microbial dysbiosis in the skin microbiome and its psychological consequences

A Borrego-Ruiz, JJ Borrego - Microorganisms, 2024 - mdpi.com
The homeostasis of the skin microbiome can be disrupted by both extrinsic and intrinsic
factors, leading to a state of dysbiosis. This imbalance has been observed at the onset of …

Clinical manifestations of human exposure to fungi

M Oliveira, D Oliveira, C Lisboa, JL Boechat… - Journal of Fungi, 2023 - mdpi.com
Biological particles, along with inorganic gaseous and particulate pollutants, constitute an
ever-present component of the atmosphere and surfaces. Among these particles are fungal …