The concomitant use of herbal medicines and pharmacotherapy is wide spread. We have
reviewed the literature to determine the possible interactions between seven popular herbal …

The first clinically relevant reports of preparations of St. John's wort (SJW), a herbal medicine
with anti‐depressant effects, interacting with other drugs, altering their bioavailability and …

Herbs are often administered in combination with therapeutic drugs, raising the potential of
herb-drug interactions. An extensive review of the literature identified reported herb-drug …

This article provides an overview of the clinical evidence of interactions between herbal and
conventional medicines. Herbs involved in drug interactions–or that have been evaluated in …

Purpose Interest in the use of herbal products has grown dramatically in the Western world.
Recent estimates suggest an overall prevalence for herbal preparation use of 13% to 63 …

Adverse drug reactions affecting the liver represent an important challenge for safety in drug
development. Drugs can reproduce practically the whole spectrum of liver diseases, but …

St John's wort (SJW) extracts, prepared from the aerial parts of Hypericum perforatum,
contain numerous pharmacologically active ingredients, including naphthodianthrones (eg …

Aims The aim of this systematic review was to assess the published clinical evidence on
interactions between herbal and conventional drugs. Methods Four electronic databases …

P‐glycoprotein (Pgp) is a 170 kDa phosphorylated glycoprotein encoded by human MDR1
gene. It is responsible for the systemic disposition of numerous structurally and …

Hypericum perforatum (Hypericaceae), known as Saint John's wort (SJW), has been used in
different systems of traditional medicine such as Chinese traditional medicine, Greek …