Designing a novel chimeric multi-epitope vaccine subunit against Staphylococcus argenteus through artificial intelligence approach integrating pan-genome analysis …

M Naveed, S Mahmood, T Aziz, A Azeem… - Journal of …, 2024 - Taylor & Francis
Staphylococcus argenteus is a newly identified pathogen that causes respiratory tract
infections, skin infections, such as cellulitis, abscesses, and impetigo, and currently, there is …

Computational Modeling, High-Level Soluble Expression and In Vitro Cytotoxicity Assessment of Recombinant Pseudomonas aeruginosa Azurin: A Promising Anti …

S Aslam, HM Rehman, MZ Sarwar, A Ahmad, N Ahmed… - Pharmaceutics, 2023 - mdpi.com
Azurin is a natural protein produced by Pseudomonas aeruginosa that exhibits potential anti-
tumor, anti-HIV, and anti-parasitic properties. The current study aimed to investigate the …

In silico investigation of a chimeric IL24-LK6 fusion protein as a potent candidate against breast cancer

H Muhammad Rehman, HM Rehman… - … and Biology Insights, 2023 - journals.sagepub.com
Targeted delivery of therapeutic anticancer chimeric molecules enhances the efficacy of
drug by improving cellular uptake and circulation time. Engineering the molecules to …

Exploring optimal drug targets through subtractive proteomics analysis and pangenomic insights for tailored drug design in tuberculosis

MF Khan, A Ali, HM Rehman, S Noor Khan… - Scientific Reports, 2024 - nature.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis, ranks among the top causes of
global human mortality, as reported by the World Health Organization's 2022 TB report. The …

Anti-inflammatory and anti-diabetic properties of indanone derivative isolated from Fernandoa adenophylla in vitro and in silico studies

A Rauf, U Rashid, ZA Shah, AA Khalil, M Shah… - Scientific Reports, 2024 - nature.com
Fernandoa adenophylla, due to the presence of phytochemicals, has various beneficial
properties and is used in folk medicine to treat many conditions. This study aimed to isolate …

Investigation of Cissus populnea as a Potential Therapeutic Agent for Erectile Dysfunction

MO Akinjiyan, OO Elekofehinti, AO Oluwatuyi… - Cell Biochemistry and …, 2024 - Springer
Cissus populnea (CP) is a plant reported to possess an erection-enhancing ability, though
mechanisms remain unclear. Drugs targeting phosphodiesterase 5 (PDE5) inhibition, such …

XRD/DFT, Hirshfeld surface analysis and molecular modelling simulations for unfolding reactivity of newly synthesized vanillin derivatives: excellent optical, NLO and …

SK Mohamed, A Ahsin, HM Rehman… - Journal of …, 2024 - Taylor & Francis
New vanillin derivatives, namely, ethyl (4-formyl-2-methoxyphenoxy) acetate (2a) and 2-(4-
formyl-2-methoxyphenoxy)-N-phenylacetamide (2b), respectively, were synthesized and …

Computational Investigation of Potent EGFR Inhibitors from Flavonoid-Based Phytochemical Constituents of Caralluma Europaea as Pancreatic Cancer Agents

K El Khatabi, M Alaqarbeh, HM Rehman… - Physical Chemistry …, 2024 - physchemres.org
The present study aims to identify effective bioactive compounds from Caralluma europaea
as potential inhibitors of EGFR. Five Caralluma europaea compounds previously evaluated …

[PDF][PDF] In silico Design and Evaluation of Novel Cell Targeting Melittin-Interleukin-24 Fusion Protein: A Potential Drug Candidate Against Breast Cancer

HM Rehman, HM Rehman, N Ahmed… - Sains …, 2023 - journalarticle.ukm.my
Fusion proteins are designed to achieve new functionality or improved properties
synergistically by incorporating multiple protein domains into one complex. The fusion of two …

FISIOLOGI ENDOKRIN

I Ujianti, C Ashilah, R Fadhilla - 2023 - repository.penerbitwidina.com
Irena Ujianti merupakan dosen fisiologi kedokteran di Fakultas Kedokteran Universitas
Muhammadiyah Prof. Dr. Hamka. Irena meraih gelar Doktor di bidang fisiologi dari Fakultas …