CC chemokines (or β-chemokines) are 28 chemotactic cytokines with an N-terminal CC
domain that play an important role in immune system cells, such as CD4+ and CD8+ …

The tumour microenvironment is the primary location in which tumour cells and the host
immune system interact. Different immune cell subsets are recruited into the tumour …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

It has been 10 years since the role of a chemokine receptor, CXCR4, in breast cancer
metastasis was first documented. Since then, the field of chemokines and cancer has grown …

Chemokines play a vital role in tumor progression and metastasis. Chemokines are involved
in the growth of many cancers including breast cancer, ovarian cancer, pancreatic cancer …

Chemokines and their receptors play a key role in development and homeostasis as well as
in the pathogenesis of tumors and autoimmune diseases. Chemokines are involved in the …

Chemokines are a key component of cancer-related inflammation. Chemokines and
chemokine receptors are downstream of genetic events that cause neoplastic transformation …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

The chemokines and their receptors are a superfamily of small secreted molecules that
control the migration of many cell types in the body. Several years ago it became clear that …

It is clear from large clinical studies that selected chemokine receptors are often up-
regulated in a large number of common human cancers, including those of the breast, lung …